Smart Nanoplatforms Responding to the Tumor Microenvironment for Precise Drug Delivery in Cancer Therapy

• Published in: International journal of nanomedicine Vol. 19; pp. 6253 - 6277
• Main Authors: Wang, Yujie, Deng, Tingting, Liu, Xi, Fang, Xueyang, Mo, Yongpan, Xie, Ni, Nie, Guohui, Zhang, Bin, Fan, Xiaoqin
• Format: Journal Article
• Language: English
• Published: New Zealand Dove 01.01.2024; Dove Medical Press
• Subjects: Animals; Antineoplastic Agents - administration & dosage; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; cancer therapy; drug delivery; Drug Delivery Systems - methods; Humans; Hydrogen-Ion Concentration; intelligent biomedicine; Nanoparticles - chemistry; Neoplasms - drug therapy; Review; stimulus-responsive; tumor microenvironment; Tumor Microenvironment - drug effects; intelligent biomedicine; cancer therapy; drug delivery; tumor microenvironment; stimulus-responsive

The tumor microenvironment (TME) is a complex and dynamic entity, comprising stromal cells, immune cells, blood vessels and extracellular matrix, which is intimately associated with the occurrence and development of cancers, as well as their therapy. Utilizing the shared characteristics of tumors, s...