Spray dried human and chimpanzee adenoviral-vectored vaccines are thermally stable and immunogenic in vivo
Highlights • Human and chimpanzee adenoviral-vectored vaccines spray dried in a sugar matrix. • Spray dried vaccine powders demonstrate thermostability and in vivo efficacy. • Spray dried vaccine powders when stored, cold chain-free, are stable up to 90 days.
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Published in | Vaccine Vol. 35; no. 22; pp. 2916 - 2924 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier Ltd
19.05.2017
Elsevier Limited |
Subjects | |
Online Access | Get full text |
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Summary: | Highlights • Human and chimpanzee adenoviral-vectored vaccines spray dried in a sugar matrix. • Spray dried vaccine powders demonstrate thermostability and in vivo efficacy. • Spray dried vaccine powders when stored, cold chain-free, are stable up to 90 days. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0264-410X 1873-2518 |
DOI: | 10.1016/j.vaccine.2017.04.026 |