Recent developments in anxiety, stress, and depression

Recent research in the development, analysis, and pharmacology of animal tests of state anxiety is discussed, including the use of responses to predator odours, the role of learning in modifying the anxiety measured in the plus-maze, and the roles of cholinergic, NMDA, and dopaminergic systems. Deve...

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Published inPharmacology, biochemistry and behavior Vol. 54; no. 1; pp. 3 - 12
Main Author File, Sandra E.
Format Journal Article Conference Proceeding
LanguageEnglish
Published New York, NY Elsevier Inc 01.05.1996
Elsevier Science
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Abstract Recent research in the development, analysis, and pharmacology of animal tests of state anxiety is discussed, including the use of responses to predator odours, the role of learning in modifying the anxiety measured in the plus-maze, and the roles of cholinergic, NMDA, and dopaminergic systems. Developmental and genetic factors are considered with particular reference to the development of tests of trait anxiety. The roles of 5-HT 1A receptors in anxiety, depression, impulsivitity, and agonistic behaviours are discussed. Recent studies on the impacts of stress on neurotransmitter, endocrine, and immune systems and the interactions between these systems are discussed, with particular emphasis on their contributions to the development of pathologic states relevant to anxiety and depression.
AbstractList Recent research in the development, analysis, and pharmacology of animal tests of state anxiety is discussed, including the use of responses to predator odours, the role of learning in modifying the anxiety measured in the plus-maze, and the roles of cholinergic, NMDA, and dopaminergic systems. Developmental and genetic factors are considered with particular reference to the development of tests of trait anxiety. The roles of 5-HT sub(1A) receptors in anxiety, depression, impulsivitity, and agonistic behaviours are discussed. Recent studies on the impacts of stress on neurotransmitter, endocrine, and immune systems and the interactions between these systems are discussed, with particular emphasis on their contributions to the development of pathologic states relevant to anxiety and depression.
Recent research in the development, analysis, and pharmacology of animal tests of state anxiety is discussed, including the use of responses to predator odours, the role of learning in modifying the anxiety measured in the plus-maze, and the roles of cholinergic, NMDA, and dopaminergic systems. Developmental and genetic factors are considered with particular reference to the development of tests of trait anxiety. The roles of 5-HT1A receptors in anxiety, depression, impulsivitity, and agonistic behaviours are discussed. Recent studies on the impacts of stress on neurotransmitter, endocrine, and immune systems and the interactions between these systems are discussed, with particular emphasis on their contributions to the development of pathologic states relevant to anxiety and depression.
Recent research in the development, analysis, and pharmacology of animal tests of state anxiety is discussed, including the use of responses to predator odours, the role of learning in modifying the anxiety measured in the plus-maze, and the roles of cholinergic, NMDA, and dopaminergic systems. Developmental and genetic factors are considered with particular reference to the development of tests of trait anxiety. The roles of 5-HT 1A receptors in anxiety, depression, impulsivitity, and agonistic behaviours are discussed. Recent studies on the impacts of stress on neurotransmitter, endocrine, and immune systems and the interactions between these systems are discussed, with particular emphasis on their contributions to the development of pathologic states relevant to anxiety and depression.
Author File, Sandra E.
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IsPeerReviewed true
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Issue 1
Keywords Depression
Anxiety
Immune function
Glucocorticoids
Stress
Animal tests
Mood disorder
Animal model
Psychotropic
Anxiety disorder
Review
Screening test
Biological activity
Tranquillizer
Animal
Antidepressant agent
5-HT1A receptor
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Snippet Recent research in the development, analysis, and pharmacology of animal tests of state anxiety is discussed, including the use of responses to predator...
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SubjectTerms Animal tests
Animals
Anxiety
Anxiety - metabolism
Anxiety - physiopathology
Anxiety - psychology
Biological and medical sciences
Depression
Depression - metabolism
Depression - physiopathology
Depression - psychology
Glucocorticoids
Humans
Immune function
Medical sciences
Neuropharmacology
Pharmacology. Drug treatments
Psycholeptics: tranquillizer, neuroleptic
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Stress
Stress, Psychological - metabolism
Stress, Psychological - physiopathology
Stress, Psychological - psychology
Title Recent developments in anxiety, stress, and depression
URI https://dx.doi.org/10.1016/0091-3057(95)02175-2
https://www.ncbi.nlm.nih.gov/pubmed/8728533
https://search.proquest.com/docview/16425253
https://search.proquest.com/docview/78165254
Volume 54
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