The trend of small cell lung cancer among young men

• Published in: Lung cancer (Amsterdam, Netherlands) Vol. 57; no. 1; pp. 34 - 36
• Main Authors: Elci, Omur Cinar, Akpinar-Elci, Muge
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 01.07.2007; Elsevier Science
• Subjects: Adult; Age Factors; Biological and medical sciences; Carcinoma, Non-Small-Cell Lung - diagnosis; Carcinoma, Non-Small-Cell Lung - epidemiology; Carcinoma, Non-Small-Cell Lung - pathology; Carcinoma, Squamous Cell - diagnosis; Carcinoma, Squamous Cell - epidemiology; Carcinoma, Squamous Cell - pathology; Hematology, Oncology and Palliative Medicine; Humans; Lung cancer; Lung Neoplasms - diagnosis; Lung Neoplasms - epidemiology; Lung Neoplasms - pathology; Male; Medical sciences; Middle Aged; Pneumology; Pulmonary/Respiratory; Retrospective Studies; Risk Factors; Small cell; Smoking - epidemiology; Time Factors; Tumors; Tumors of the respiratory system and mediastinum; Turkey - epidemiology; Young; Turkey; Small cell; Young; Lung cancer; Human; Lung disease; Respiratory disease; Trend; Male; Malignant tumor; Cancerology; Young adult; Bronchus disease; Small cell carcinoma; Cell; Pneumology
• ISSN: 0169-5002; 1872-8332
• DOI: 10.1016/j.lungcan.2007.02.013

Summary In this report, we investigated the distribution of histologic types of lung cancer by age in Turkey. Among 1354 lung cancer cases diagnosed in Social Security Agency Okmeydani Hospital, Istanbul, Turkey, we included 912 male cases with data on age, smoking status, and histopathologic type. We calculated the smoking-adjusted risk for histopathologic types by age. A majority of the cases were between 45 and 64 years of age (70.5%). The smoking-adjusted risk of squamous cell carcinoma increased with advancing age, while the risk of small cell carcinoma decreased with age. The risk of small cell carcinoma was 1.6 times higher among men younger than 45 years of age compared to older men (odds ratios (OR): 1.6, 95% confidence intervals (CI): 1.1–2.3). In conclusion, we found a significant decreasing trend for small cell carcinoma by increasing age, which resulted with an excess risk among men younger than age 45.