Outcomes for intermediate risk prostate cancer: Are there advantages for surgery, external radiation, or brachytherapy?

• Published in: Urologic oncology Vol. 27; no. 1; pp. 67 - 71
• Main Authors: Klein, Eric A., M.D, Ciezki, Jay, M.D, Kupelian, Patrick A., M.D, Mahadevan, Arul, M.D
• Format: Journal Article Conference Proceeding
• Language: English
• Published: New York, NY Elsevier Inc 2009; Elsevier
• Subjects: Biological and medical sciences; Brachytherapy; Brachytherapy - methods; Disease-Free Survival; External radiation; Humans; Male; Medical Oncology - methods; Medical sciences; Nephrology. Urinary tract diseases; Prostate cancer; Prostatectomy - methods; Prostatic Neoplasms - radiotherapy; Prostatic Neoplasms - surgery; Quality of Life; Radical prostatectomy; Radiotherapy - methods; Risk; Time Factors; Treatment Outcome; Tumors; Tumors of the urinary system; Urinary tract. Prostate gland; Urology; Brachytherapy; Radical prostatectomy; External radiation; Prostate cancer; Quality of life; Nephrology; Urinary system disease; Prognosis; Prostate disease; Radiosurgery; Malignant tumor; Radiotherapy; Urology; Cancerology; Treatment; Advantage; Surgery; Risk factor; External; Prostatectomy; Male genital diseases; Curietherapy; Cancer
• ISSN: 1078-1439; 1873-2496
• DOI: 10.1016/j.urolonc.2008.04.001

Abstract The treatment of localized prostate cancer remains controversial because of the lack of conclusive well-controlled or randomized studies comparing outcome of various forms of radiotherapy (RT) to radical prostatectomy (RP). We review recent results from an institutional database and prospective quality of life study comparing cancer-related and quality of live (QOL) outcomes among different treatment modalities for intermediate risk prostate cancer. The results suggest similar short-term survival but domain-specific effects on QOL after treatment with radical prostatectomy, brachytherapy, or external beam radiotherapy.