A Photothermal Therapy Strategy for Monitoring Real-Time Temperature in Kidney Cancers by Injecting Gold Nanorods with Phosphors

Photothermal ablation therapy (PTA) has been widely reported; however, it is not possible to predict the internal temperature of the tumor in real time that causes ineffective treatment and normal tissue burns. Here, we have designed a photothermal therapy strategy under real-time temperature monito...

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Bibliographic Details
Published inJournal of biomedical nanotechnology Vol. 17; no. 3; p. 501
Main Authors Shen, Wenzeng, Zhang, Xuefeng, Liu, Dongyang, Xing, Christina, Tucker, Isabelle, Amador, Eric, Chen, Wei, Yang, Yanmin
Format Journal Article
LanguageEnglish
Published United States 01.03.2021
Subjects
Cell Line, Tumor
Gold
Humans
Kidney Neoplasms
Nanotubes
Phototherapy
Photothermal Therapy
Temperature
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Summary:Photothermal ablation therapy (PTA) has been widely reported; however, it is not possible to predict the internal temperature of the tumor in real time that causes ineffective treatment and normal tissue burns. Here, we have designed a photothermal therapy strategy under real-time temperature monitoring by injecting gold nanorods (AuNRs) and NaYF₄: Yb ₄ phosphors to monitor the temperature inside the tumor. Our experiments confirm the effectiveness of this strategy, which is expected to be an aid in the development of real-time temperature monitoring and effective photothermal therapy for the treatment of cancers.
ISSN:1550-7033
DOI:10.1166/jbn.2021.3009