Treatment of ranula in pediatric patients with intralesional injection of OK-432

To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432. Retrospective analysis of 13 cases. Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005. Among 13 cases, 9 were completely regressed by inj...

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Bibliographic Details
Published inThe Laryngoscope Vol. 116; no. 6; p. 966
Main Authors Lee, Heung-Man, Lim, Hyun-Woo, Kang, Hee Joon, Chae, Sung-Won, Hwang, Soon-Jae, Jung, Kwang-Yoon, Woo, Jeong-Soo
Format Journal Article
LanguageEnglish
Published United States 01.06.2006
Subjects
Adolescent
Child
Female
Humans
Injections, Intralesional
Male
Picibanil - administration & dosage
Ranula - drug therapy
Retrospective Studies
Sclerosing Solutions - administration & dosage
Treatment Outcome
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Summary:To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432. Retrospective analysis of 13 cases. Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005. Among 13 cases, 9 were completely regressed by injection therapy alone. Three cases were incompletely regressed. One case was cured by surgical excision. The follow-up duration was 6 to 46 (mean 24.3) months. Adverse effects of OK-432 injection were tolerable, and no complication was observed. On the basis of our experience, sclerotherapy with OK-432 was a safe and effective primary treatment for a ranula in children. Further study will be needed to conclude its long-term effectiveness.
ISSN:0023-852X
1531-4995
DOI:10.1097/01.Mlg.0000216809.90196.83