Regional abnormalities of myocardial deformation in patients with hypertrophic cardiomyopathy: correlations with delayed enhancement in cardiac magnetic resonance

• Published in: European journal of heart failure Vol. 11; no. 10; pp. 952 - 957
• Main Authors: Ghio, Stefano, Revera, Miriam, Mori, Francesca, Klersy, Catherine, Raisaro, Arturo, Raineri, Claudia, Serio, Alessandra, Pasotti, Michele, Visconti, Luigi Oltrona
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.10.2009; Oxford University Press
• Subjects: Adult; Aged; Cardiac magnetic resonance; Cardiomyopathy, Hypertrophic - diagnosis; Case-Control Studies; Confidence Intervals; Echocardiography, Doppler - methods; Female; Follow-Up Studies; Gadolinium; Humans; Hypertrophic cardiomyopathy; Image Enhancement - methods; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging - methods; Male; Middle Aged; Myocardium - pathology; Probability; Reference Values; Risk Assessment; Systolic deformation; Tissue-doppler imaging; Ventricular Dysfunction, Left - diagnosis; Hypertrophic cardiomyopathy; Tissue-Doppler imaging; Systolic deformation; Cardiac magnetic resonance

Aims Hypertrophic cardiomyopathy (HCM) is a genetic disease histologically characterized by a profound disarray of myocardial fibres and by local fibrosis. We sought to characterize regional left ventricular contractility in HCM patients using deformation analysis and to compare it with the presence...