A chronic non‐healing ulcer plantar

Acral melanoma is challenging in two ways: it is in some cases difficult to diagnose and, once metastases have occurred, the prognosis is poor as therapy is less effective compared to melanoma from other parts of the skin. Here we report a case, were the correct diagnosis was made after melanoma has...

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Published inSkin health and disease Vol. 4; no. 1; pp. e280 - n/a
Main Authors Unterluggauer, Luisa, Okamoto, Ichiro
Format Journal Article
LanguageEnglish
Published England John Wiley & Sons, Inc 01.02.2024
John Wiley and Sons Inc
Wiley
Subjects
Amputation
Biopsy
Images in Dermatology
Lymphatic system
Melanoma
Metastasis
Ulcers
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Summary:Acral melanoma is challenging in two ways: it is in some cases difficult to diagnose and, once metastases have occurred, the prognosis is poor as therapy is less effective compared to melanoma from other parts of the skin. Here we report a case, were the correct diagnosis was made after melanoma has spread already to distant sites. Instead of surgery, we decided to start with immunotherapy consisting of Ipilimumab and Nivolumab. A complete response could be achieved without surgery of any tumors, including the primary melanoma. A 70‐year‐old woman presented with an ulcerating lesion on her right foot which has been treated as a nonhealing‐ulcer for 3 years. A representative biopsy revealed the diagnosis of an acral stage IV melanoma.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:2690-442X
2690-442X
DOI:10.1002/ski2.280