Second primary malignant peripheral nerve sheath tumor of the paranasal sinuses after nasopharynx carcinoma

Malignant peripheral nerve sheath tumors are uncommon neoplasms that arise out of Schwann cells from the peripheral nerves, which rarely occur in the paranasal sinuses and nasal cavity. Especially with the increasing long-term survival of patients with nasopharynx carcinoma, second primary cancers c...

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Bibliographic Details
Published inThe Journal of craniofacial surgery Vol. 25; no. 6; p. 2074
Main Authors Eryilmaz, Mehmet Akif, Varsak, Yasin Kürşad, Gul, Zuhal, Etli, Özlem
Format Journal Article
LanguageEnglish
Published United States 01.11.2014
Subjects
Carcinoma
Fatal Outcome
Humans
Male
Middle Aged
Nasopharyngeal Carcinoma
Nasopharyngeal Neoplasms - pathology
Neoplasms, Second Primary
Nerve Sheath Neoplasms - pathology
Nose Neoplasms - pathology
Paranasal Sinuses - pathology
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Summary:Malignant peripheral nerve sheath tumors are uncommon neoplasms that arise out of Schwann cells from the peripheral nerves, which rarely occur in the paranasal sinuses and nasal cavity. Especially with the increasing long-term survival of patients with nasopharynx carcinoma, second primary cancers can be diagnosed. Second primary cancers are not uncommon in patients with the prior radiation therapy. However, malignant peripheral nerve sheath tumor in the head and neck region after radiation is an exceedingly rare condition. We report the first case of malignant peripheral nerve sheath tumor of the paranasal sinuses as a second primary malignancy in a patient treated with radiation therapy for nasopharyngeal carcinoma 10 years ago.
ISSN:1536-3732
DOI:10.1097/SCS.0000000000000912