canSAR: an updated cancer research and drug discovery knowledgebase

canSAR (http://cansar.icr.ac.uk) is a publicly available, multidisciplinary, cancer-focused knowledgebase developed to support cancer translational research and drug discovery. canSAR integrates genomic, protein, pharmacological, drug and chemical data with structural biology, protein networks and d...

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Published inNucleic acids research Vol. 44; no. D1; pp. D938 - D943
Main Authors Tym, Joseph E, Mitsopoulos, Costas, Coker, Elizabeth A, Razaz, Parisa, Schierz, Amanda C, Antolin, Albert A, Al-Lazikani, Bissan
Format Journal Article
LanguageEnglish
Published England Oxford University Press 04.01.2016
Subjects
Animals
Antineoplastic Agents - pharmacology
Cell Line, Tumor
Clinical Trials as Topic
Database Issue
Drug Discovery
Gene Expression
Humans
Knowledge Bases
Neoplasm Proteins - chemistry
Neoplasm Proteins - genetics
Neoplasm Proteins - metabolism
Neoplasms - genetics
Neoplasms - metabolism
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Summary:canSAR (http://cansar.icr.ac.uk) is a publicly available, multidisciplinary, cancer-focused knowledgebase developed to support cancer translational research and drug discovery. canSAR integrates genomic, protein, pharmacological, drug and chemical data with structural biology, protein networks and druggability data. canSAR is widely used to rapidly access information and help interpret experimental data in a translational and drug discovery context. Here we describe major enhancements to canSAR including new data, improved search and browsing capabilities, new disease and cancer cell line summaries and new and enhanced batch analysis tools.
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ISSN:0305-1048
1362-4962
DOI:10.1093/nar/gkv1030