First-Generation Autologous Chondrocyte Implantation in Patients With Cartilage Defects of the Knee: 7 to 14 Years' Clinical and Magnetic Resonance Imaging Follow-up Evaluation

• Published in: Arthroscopy Vol. 28; no. 12; pp. 1851 - 1861
• Main Authors: Moradi, Babak, M.D, Schönit, Eva, M.D, Nierhoff, Corinna, M.D, Hagmann, Sébastien, M.D, Oberle, Doris, M.D., Ph.D, Gotterbarm, Tobias, M.D, Schmitt, Holger, M.D., Ph.D, Zeifang, Felix, M.D., Ph.D
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.12.2012; Elsevier
• Subjects: Adolescent; Adult; Age Factors; Arthroscopy; Biological and medical sciences; Cartilage, Articular - injuries; Cartilage, Articular - surgery; Cell Transplantation; Chondrocytes - transplantation; Contraindications; Endoscopy; Female; Follow-Up Studies; Humans; Investigative techniques, diagnostic techniques (general aspects); Knee Joint - surgery; Magnetic Resonance Imaging; Male; Medical sciences; Middle Aged; Orthopedic surgery; Orthopedics; Osteochondrosis - surgery; Patient Satisfaction; Retrospective Studies; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Time Factors; Tissue and Organ Harvesting - methods; Treatment Outcome; Young Adult; Knee; Human; Cartilage; Autograft; Chondrocyte implantation; Arthroscopy; Orthopedic surgery; Treatment; Medical imagery; Endoscopy; Nuclear magnetic resonance imaging

Purpose The purpose of this study was to evaluate the overall long-term improvement of autologous chondrocyte implantation (ACI) treatment in terms of patient satisfaction, clinical assessment, and magnetic resonance imaging (MRI) evaluation. Furthermore, we aimed to assess the impact of independent...