Dupuytren’s Disease susceptibility gene, EPDR1, is involved in myofibroblast contractility
Highlights • All three EPDR1 transcripts are detected in affected Dupuytren’s tissue. • Dupuytren’s tissue contracts more in the FPCL paradigm. • Knockdown of EPDR1 moderately attenuates late stage of contraction rate in FPCL.
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Published in | Journal of dermatological science Vol. 83; no. 2; pp. 131 - 137 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier Ireland Ltd
01.08.2016
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Subjects | |
Online Access | Get full text |
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Summary: | Highlights • All three EPDR1 transcripts are detected in affected Dupuytren’s tissue. • Dupuytren’s tissue contracts more in the FPCL paradigm. • Knockdown of EPDR1 moderately attenuates late stage of contraction rate in FPCL. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0923-1811 1873-569X |
DOI: | 10.1016/j.jdermsci.2016.04.015 |