Two solutions for registration of ultrasound to MRI for image-guided prostate interventions

• Published in: 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society Vol. 2012; pp. 1129 - 1132
• Main Authors: Moradi, M., Janoos, F., Fedorov, A., Risholm, P., Kapur, T., Wolfsberger, L. D., Nguyen, P. L., Tempany, C. M., Wells, W. M.
• Format: Conference Proceeding Journal Article
• Language: English
• Published: United States IEEE 01.01.2012
• Subjects: Biomedical imaging; Brachytherapy; Glands; Humans; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Models, Biological; Prostate - diagnostic imaging; Prostate - surgery; Prostatic Neoplasms - diagnostic imaging; Prostatic Neoplasms - surgery; Radiography; Splines (mathematics); Ultrasonic imaging; Ultrasonography, Interventional - methods
• ISBN: 1424441196; 9781424441198
• ISSN: 1094-687X; 1557-170X; 1558-4615
• DOI: 10.1109/EMBC.2012.6346134

Ultrasound-guided prostate interventions could benefit from incorporating the radiologic localization of the tumor which can be acquired from multiparametric MRI. To enable this integration, we propose and compare two solutions for registration of T2 weighted MR images with transrectal ultrasound. Firstly, we propose an innovative and practical approach based on deformable registration of binary label maps obtained from manual segmentation of the gland in the two modalities. This resulted in a target registration error of 3.6±1.7 mm. Secondly, we report a novel surface-based registration method that uses a biomechanical model of the tissue and results in registration error of 3.2±1.3 mm. We compare the two methods in terms of accuracy, clinical use and technical limitations.