Current status of chemokine receptor inhibitors in development

Highlights ► Innovative drugs targeting CXC and CC receptors. ► Preclinical and clinical development of drugs acting on chemokine system. ► Perspectives on the development of novel Small Molecular Weight chemokine inhibitors.

Saved in:
Bibliographic Details
Published inImmunology letters Vol. 145; no. 1; pp. 68 - 78
Main Authors Allegretti, Marcello, Cesta, Maria Candida, Garin, Alexandre, Proudfoot, Amanda E.I
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 30.07.2012
Subjects
Allergy and Immunology
Allosteric inhibitors
Animals
Autoimmune diseases
CC receptor antagonists
Cell Movement - drug effects
Chemokine
Chemokine receptors
Chemokines - immunology
Clinical trials
Clinical Trials as Topic
CXC
Drug Discovery
HIV
Humans
Inflammation
Inflammatory diseases
Metastases
Molecular Targeted Therapy
Pharmaceuticals
Receptors, Chemokine - antagonists & inhibitors
Small Molecule Libraries
Tumors
Chemokine
Allosteric inhibitors
HIV
CC receptor antagonists
Inflammatory diseases
CXC
Online AccessGet full text

Cover

More Information
Summary:Highlights ► Innovative drugs targeting CXC and CC receptors. ► Preclinical and clinical development of drugs acting on chemokine system. ► Perspectives on the development of novel Small Molecular Weight chemokine inhibitors.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ObjectType-Feature-1
ISSN:0165-2478
1879-0542
DOI:10.1016/j.imlet.2012.04.003