Nonlinear Effects in Rh-Catalyzed Asymmetric Olefin Hydrogenation Using Mixtures of Chiral Monodentate P Ligands

Well mixed: A 1:1 mixture of two different binaphthol‐derived monophosphonite ligands (L) is employed in the Rh‐catalyzed hydrogenation of prochiral olefins (see scheme; cod=cyclooctadiene). Variation of the enantiopurity of the ligands results in unusual nonlinear effects; furthermore, >92 % ee...

Full description

Saved in:
Bibliographic Details
Published inAngewandte Chemie International Edition Vol. 45; no. 9; pp. 1412 - 1415
Main Authors Reetz, Manfred T., Fu, Yu, Meiswinkel, Andreas
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 20.02.2006
WILEY‐VCH Verlag
Subjects
asymmetric catalysis
hydrogenation
kinetics
nonlinear effects
rhodium
Online AccessGet full text

Cover

More Information
Summary:Well mixed: A 1:1 mixture of two different binaphthol‐derived monophosphonite ligands (L) is employed in the Rh‐catalyzed hydrogenation of prochiral olefins (see scheme; cod=cyclooctadiene). Variation of the enantiopurity of the ligands results in unusual nonlinear effects; furthermore, >92 % ee can be achieved even if one component is racemic.
Bibliography:istex:4AD577076769DA9C8C65D4DB15ECA991A304FFAD
ark:/67375/WNG-PPWV3LFX-8
We thank the Fonds der Chemischen Industrie for generous support and Nils Theyssen for advice in measuring the hydrogenation rates.
ArticleID:ANIE200503604
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200503604