Functional Ion Channels in Tethered Bilayer Membranes-Implications for Biosensors
The ties that bind. A biosensor based on modulation of single ion‐channel activity, with the ability to detect analytes in the micromolar range was devised. Ion channels were interfaced to a gold surface and reconstituted into tethered bilayer lipid membranes (tBLMs; see scheme). Using this method w...
Saved in:
| Published in | Chembiochem : a European journal of chemical biology Vol. 8; no. 11; pp. 1246 - 1250 |
|---|---|
| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Weinheim
WILEY-VCH Verlag
23.07.2007
WILEY‐VCH Verlag |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The ties that bind. A biosensor based on modulation of single ion‐channel activity, with the ability to detect analytes in the micromolar range was devised. Ion channels were interfaced to a gold surface and reconstituted into tethered bilayer lipid membranes (tBLMs; see scheme). Using this method we obtained single channel activities from the synthetic ion channel, M2δ, and the Ca2+‐activated K+ ion channel. |
|---|---|
| AbstractList | The ties that bind. A biosensor based on modulation of single ion‐channel activity, with the ability to detect analytes in the micromolar range was devised. Ion channels were interfaced to a gold surface and reconstituted into tethered bilayer lipid membranes (tBLMs; see scheme). Using this method we obtained single channel activities from the synthetic ion channel, M2δ, and the Ca2+‐activated K+ ion channel. |
| Author | Long, Joanna R. Andersson, Martin Price, Rebecca B. Anderson, Peter A. V. Dorvel, Brian R. Fine, Daniel Duran, Randolph S. Knoll, Wolfgang Dodabalapur, Ananth Köper, Ingo Keizer, Henk M. |
| Author_xml | – sequence: 1 givenname: Henk M. surname: Keizer fullname: Keizer, Henk M. organization: Department of Chemistry, University of Florida, Leigh Hall, Gainesville, FL 32611, USA, Fax: (+1) 352-392-9741 – sequence: 2 givenname: Brian R. surname: Dorvel fullname: Dorvel, Brian R. organization: Department of Chemistry, University of Florida, Leigh Hall, Gainesville, FL 32611, USA, Fax: (+1) 352-392-9741 – sequence: 3 givenname: Martin surname: Andersson fullname: Andersson, Martin organization: Department of Chemistry, University of Florida, Leigh Hall, Gainesville, FL 32611, USA, Fax: (+1) 352-392-9741 – sequence: 4 givenname: Daniel surname: Fine fullname: Fine, Daniel organization: Microelectronics Research Center, University of Texas at Austin, 10100 Burnet Road, Building 160, Austin, TX 78758, USA – sequence: 5 givenname: Rebecca B. surname: Price fullname: Price, Rebecca B. organization: Whitney Laboratory for Marine Bioscience and Dept. of Physiology and Functional Genomics, University of Florida, 9505 Ocean Shore Blvd, St. Augustine, FL 32080, USA – sequence: 6 givenname: Joanna R. surname: Long fullname: Long, Joanna R. organization: Dept. of Biochemistry & Molecular Biology and McKnight Brain Institute, University of Florida, P. O. Box 100244, Gainesville, FL 32610-0244, USA – sequence: 7 givenname: Ananth surname: Dodabalapur fullname: Dodabalapur, Ananth organization: Microelectronics Research Center, University of Texas at Austin, 10100 Burnet Road, Building 160, Austin, TX 78758, USA – sequence: 8 givenname: Ingo surname: Köper fullname: Köper, Ingo organization: Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany – sequence: 9 givenname: Wolfgang surname: Knoll fullname: Knoll, Wolfgang organization: Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany – sequence: 10 givenname: Peter A. V. surname: Anderson fullname: Anderson, Peter A. V. organization: Whitney Laboratory for Marine Bioscience and Dept. of Physiology and Functional Genomics, University of Florida, 9505 Ocean Shore Blvd, St. Augustine, FL 32080, USA – sequence: 11 givenname: Randolph S. surname: Duran fullname: Duran, Randolph S. email: duran@chem.ufl.edu organization: Department of Chemistry, University of Florida, Leigh Hall, Gainesville, FL 32611, USA, Fax: (+1) 352-392-9741 |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/17583881$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkDtPwzAURi0E4r0yokxsKX41dkaIeFTiIUoREotlOzfCkNjFbgX996RqBWxMvsM5R9a3hzZ98IDQEcEDgjE9tcbZAcVYYIxLvoF2CWdlLgrGNtc3p1TsoL2U3pZIwcg22iFiKJmUZBc9XM69nbngdZuNgs-qV-09tClzPpvA7BUi1Nm5a_UCYnYLnYnaQ8pH3bR1Vi_FlDUh9khI4FOI6QBtNbpNcLh-99HT5cWkus5v7q9G1dlNbjkXPCdcY9oI1phCmiFhppSMFtQaQyytNbdASEEbYjipgcpaEl5yKqkWoJnmhu2jk1V3GsPHHNJMdS5ZaNv-g2GelMCCUknKHhysQBtDShEaNY2u03GhCFbLEdVyRPUzYi8cr8tz00H9i69X64FyBXy6Fhb_5FR1Pqr-xvOV69IMvn5cHd9VIZgYque7KyVfhuPxo3xRkn0DcgCO-g |
| CitedBy_id | crossref_primary_10_1021_accountsmr_2c00181 crossref_primary_10_1039_b919988h crossref_primary_10_1021_acs_analchem_0c02720 crossref_primary_10_3390_coatings10100981 crossref_primary_10_1039_c1cp20667b crossref_primary_10_1002_smll_201906394 crossref_primary_10_1039_C2SM26850G crossref_primary_10_1111_1574_6976_12063 crossref_primary_10_1021_acsnano_0c01330 crossref_primary_10_1039_c2sm25702e crossref_primary_10_3390_ma5122637 crossref_primary_10_1149_2_0101810jes crossref_primary_10_1021_la204485n crossref_primary_10_1007_s10008_010_1284_5 crossref_primary_10_1016_j_bios_2011_11_010 crossref_primary_10_1021_la201411b crossref_primary_10_1016_j_aca_2022_340397 crossref_primary_10_1021_ja804968g crossref_primary_10_1021_acsami_3c09304 crossref_primary_10_1088_0964_1726_20_9_094020 crossref_primary_10_1016_j_abb_2010_09_029 crossref_primary_10_1002_elsa_202100180 crossref_primary_10_1021_la102719w crossref_primary_10_1016_j_bios_2012_05_013 crossref_primary_10_1016_j_elecom_2007_12_018 crossref_primary_10_3390_membranes6030036 crossref_primary_10_1016_j_bbamem_2007_10_012 crossref_primary_10_1021_nn501376z crossref_primary_10_1007_s00249_014_0998_1 crossref_primary_10_1016_j_electacta_2008_02_121 crossref_primary_10_1039_c2sm07107j crossref_primary_10_1039_c2lc20991h crossref_primary_10_1039_c0sm00631a crossref_primary_10_1016_j_aca_2010_07_001 crossref_primary_10_1039_b703980h crossref_primary_10_1109_TIM_2022_3193726 crossref_primary_10_1002_ange_201106482 crossref_primary_10_1080_10408347_2022_2088226 crossref_primary_10_1021_la800484k crossref_primary_10_1098_rsif_2014_0232 crossref_primary_10_1021_la302500r crossref_primary_10_1016_j_bbamem_2020_183232 crossref_primary_10_1109_JMEMS_2011_2153826 crossref_primary_10_1016_S1369_7021_10_70059_6 crossref_primary_10_1016_j_colsurfb_2010_10_017 crossref_primary_10_7567_1347_4065_ab0c78 crossref_primary_10_1021_acsphotonics_8b00847 crossref_primary_10_1038_s41596_019_0174_2 crossref_primary_10_1002_anie_201106482 crossref_primary_10_1002_adfm_201602123 crossref_primary_10_1039_b711066a crossref_primary_10_1016_j_cbpa_2007_09_020 crossref_primary_10_1039_C3CP55116D crossref_primary_10_1016_j_biochi_2018_11_011 |
| Cites_doi | 10.1016/S0021-9258(17)42402-1 10.1016/S0005-2736(02)00575-8 10.1085/jgp.84.1.1 10.1021/la0342060 10.1002/(SICI)1521-3757(19990201)111:3<402::AID-ANGE402>3.0.CO;2-D 10.1085/jgp.20028721 10.1038/35093038 10.1073/pnas.85.22.8703 10.1021/la063503c 10.1021/la052534p 10.1016/S0006-3495(04)74171-5 10.1002/ange.200390048 10.1002/(SICI)1521-3773(19990201)38:3<389::AID-ANIE389>3.0.CO;2-U 10.1016/S0006-3495(87)83298-8 10.1085/jgp.116.1.75 10.1126/science.7687074 10.1016/S0006-3495(94)80883-5 10.1093/toxsci/kfh269 10.1529/biophysj.106.083592 10.1002/anie.200390080 10.1016/S0006-3495(94)80881-1 10.1038/353846a0 10.1021/la034197v 10.1038/42432 10.1085/jgp.20028605 |
| ContentType | Journal Article |
| Copyright | Copyright © 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim |
| Copyright_xml | – notice: Copyright © 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim |
| DBID | BSCLL CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
| DOI | 10.1002/cbic.200700094 |
| DatabaseName | Istex Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Anatomy & Physiology Chemistry |
| EISSN | 1439-7633 |
| EndPage | 1250 |
| ExternalDocumentID | 10_1002_cbic_200700094 17583881 CBIC200700094 ark_67375_WNG_8Z5RRS8Z_8 |
| Genre | shortCommunication Journal Article |
| GrantInformation_xml | – fundername: NSF REU program – fundername: AFOSR – fundername: Knut and Alice Wallenbergs Foundation – fundername: DARPA MOLDICE program |
| GroupedDBID | --- -DZ -~X 05W 0R~ 1L6 1OC 29B 33P 3WU 4.4 4ZD 50Y 53G 5GY 5VS 66C 6J9 6P2 77Q 8-0 8-1 8UM A00 AAESR AAHHS AAIHA AANLZ AASGY AAXRX AAZKR ABCUV ABIJN ABJNI ABLJU ACAHQ ACBWZ ACCFJ ACCZN ACGFS ACIWK ACPOU ACPRK ACXBN ACXQS ADBBV ADKYN ADMGS ADOZA ADXAS ADZMN ADZOD AEEZP AEGXH AEIGN AENEX AEQDE AEUQT AEUYR AFBPY AFFNX AFFPM AFGKR AFRAH AFZJQ AHBTC AHMBA AITYG AIURR AIWBW AJBDE ALMA_UNASSIGNED_HOLDINGS ALUQN AMYDB ASPBG AVWKF AZFZN AZVAB BDRZF BFHJK BMXJE BRXPI BSCLL CS3 DCZOG DPXWK DR2 DRFUL DRSTM DU5 EBS EJD F5P FEDTE G-S GNP GODZA HBH HGLYW HHY HHZ HVGLF HZ~ IH2 IX1 JPC KQQ LATKE LAW LEEKS LITHE LOXES LUTES LYRES MEWTI MXFUL MXSTM MY~ NNB O9- OIG P2P P2W P4E PQQKQ R.K ROL RWI RX1 SUPJJ V2E W99 WBKPD WH7 WJL WOHZO WXSBR WYJ XPP XV2 Y6R YZZ ZZTAW ~KM ~S- CGR CUY CVF ECM EIF NPM AAMNL AAYXX ACRPL ACYXJ CITATION 7X8 |
| ID | FETCH-LOGICAL-c4474-14a02f73fb68b513b983262cbb1c2da4ce1162f1b41de28d81494282a7ea3a4b3 |
| IEDL.DBID | DR2 |
| ISSN | 1439-4227 |
| IngestDate | Wed Dec 04 07:49:47 EST 2024 Fri Dec 06 04:53:08 EST 2024 Sat Sep 28 07:46:26 EDT 2024 Sat Aug 24 00:56:31 EDT 2024 Wed Oct 30 09:50:31 EDT 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 11 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c4474-14a02f73fb68b513b983262cbb1c2da4ce1162f1b41de28d81494282a7ea3a4b3 |
| Notes | DARPA MOLDICE program NSF REU program ArticleID:CBIC200700094 Knut and Alice Wallenbergs Foundation ark:/67375/WNG-8Z5RRS8Z-8 AFOSR istex:71CE4B982BF89A3E8EAFCBD62D84064B0F36DE00 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PMID | 17583881 |
| PQID | 70722819 |
| PQPubID | 23479 |
| PageCount | 5 |
| ParticipantIDs | proquest_miscellaneous_70722819 crossref_primary_10_1002_cbic_200700094 pubmed_primary_17583881 wiley_primary_10_1002_cbic_200700094_CBIC200700094 istex_primary_ark_67375_WNG_8Z5RRS8Z_8 |
| PublicationCentury | 2000 |
| PublicationDate | July 23, 2007 |
| PublicationDateYYYYMMDD | 2007-07-23 |
| PublicationDate_xml | – month: 07 year: 2007 text: July 23, 2007 day: 23 |
| PublicationDecade | 2000 |
| PublicationPlace | Weinheim |
| PublicationPlace_xml | – name: Weinheim – name: Germany |
| PublicationTitle | Chembiochem : a European journal of chemical biology |
| PublicationTitleAlternate | ChemBioChem |
| PublicationYear | 2007 |
| Publisher | WILEY-VCH Verlag WILEY‐VCH Verlag |
| Publisher_xml | – name: WILEY-VCH Verlag – name: WILEY‐VCH Verlag |
| References | T. Stora, J. H. Lakey, H. Vogel, Angew. Chem. 1999, 111, 402 B. S. Rothberg, K. L. Magleby, J. Gen. Physiol. 2000, 116, 75. G. Pérez, A. Lagrutta, J. P. Adelman, L. Toro, Biophys. J. 1994, 66, 1022. Angew. Chem. Int. Ed. 1999, 38, 389. H. Bayley, P. S. Cremer, Nature 2001, 413, 226. F. T. Horrigan, R. W. Aldrich, J. Gen. Physiol. 2002, 120, 267. A. Butler, S. Tsunoda, D. P. McCobb, A. Wei, L. Salkoff, Science 1993, 261, 221. M. Garcia-Calvo, H. G. Knaus, O. B. McManus, K. M. Giangiacomo, G. J. Kaczorowski, M. L. Garcia, J. Biol. Chem. 1994, 269, 676. S. M. Schiller, R. Naumann, K. Lovejoy, H. Kunz, W. Knoll, Angew. Chem. 2003, 115, 219 S. Oiki, W. Danho, V. Madison, M. Montal, Proc. Natl. Acad. Sci. USA 1988, 85, 8703. C. J. Smulders, T. J. Bueters, S. Vailati, R. G. van Kleef, H. P. Vijverberg, Toxicol. Sci. 2004, 82, 545. W. Römer, C. Steinem, Biophys. J. 2004, 86, 955. Angew. Chem. Int. Ed. 2003, 42, 208. M. Montal, S. J. Opella, Biochim. Biophys. Acta Biomembr. 2002, 1565, 287. B. A. Cornell, V. L. B. Braach-Maksvytis, L. G. King, P. D. J. Osman, B. Raguse, L. Wieczorek, R. J. Pace, Nature 1997, 387, 580. F. J. Sigworth, S. M. Sine, Biophys. J. 1987, 52, 1047. A. L. Blatz, K. L. Magleby, J. Gen. Physiol. 1984, 84, 1. F. Revah, D. Bertrand, J. L. Galzi, A. Devillers-Thiery, C. Mulle, N. Hussy, S. Bertrand, M. Ballivet, J. P. Changeux, Nature 1991, 353, 846. R. Naumann, S. M. Schiller, F. Giess, B. Grohe, K. B. Hartman, I. Kärcher, I. Köper, J. Lübben, K. Vasilev, W. Knoll, Langmuir 2003, 19, 5435. M. Andersson, H. M. Keizer, C. Zhu, D. Fine, A. Dodabalapur, R. S. Duran, Langmuir 2007, 23, 2924-2927. L. Toro, M. Wallner, P. Meera, Y. Tanaka, News Physiol. Sci. 1998, 13, 112. H. Suzuki, K. V. Tabata, H. Noji, S. Takeuchi, Langmuir 2006, 22, 1937. B. Hille, Ion Channels of Excitable Membranes, 3rd ed., Sinauer Associates, Sunderland, MA, 2001. S. Terrettaz, M. Mayer, H. Vogel, Langmuir 2003, 19, 5567. K. L. Magleby, J. Gen. Physiol. 2003, 121, 81. E. Stefani, L. Toro, E. Perozo, F. Bezanilla, Biophys. J. 1994, 66, 996. E. K. Schmitt, M. Vrouenraets, C. Steinem, Biophys. J. 2006, 91, 2163. 1984; 84 2006; 91 2004; 86 2003 2003; 115 42 1991; 353 1987; 52 1994; 269 2004; 82 2001 2002; 120 1999 1999; 111 38 2006; 22 2000; 116 2002; 1565 1997; 387 1994; 66 1993; 261 2003; 19 1988; 85 2007; 23 2003; 121 2001; 413 1998; 13 Toro L. (e_1_2_4_11_2) 1998; 13 Hille B. (e_1_2_4_9_2) 2001 e_1_2_4_20_2 e_1_2_4_22_2 e_1_2_4_24_2 e_1_2_4_23_2 e_1_2_4_25_2 e_1_2_4_2_2 e_1_2_4_1_2 e_1_2_4_4_2 e_1_2_4_3_2 e_1_2_4_6_2 Garcia‐Calvo M. (e_1_2_4_21_2) 1994; 269 e_1_2_4_4_3 e_1_2_4_5_2 e_1_2_4_8_2 e_1_2_4_7_2 e_1_2_4_10_2 e_1_2_4_12_2 e_1_2_4_13_2 e_1_2_4_14_2 e_1_2_4_15_2 e_1_2_4_17_2 e_1_2_4_16_2 e_1_2_4_18_3 e_1_2_4_19_2 e_1_2_4_18_2 |
| References_xml | – volume: 413 start-page: 226 year: 2001 publication-title: Nature – volume: 387 start-page: 580 year: 1997 publication-title: Nature – volume: 66 start-page: 1022 year: 1994 publication-title: Biophys. J. – year: 2001 – volume: 19 start-page: 5567 year: 2003 publication-title: Langmuir – volume: 85 start-page: 8703 year: 1988 publication-title: Proc. Natl. Acad. Sci. USA – volume: 19 start-page: 5435 year: 2003 publication-title: Langmuir – volume: 52 start-page: 1047 year: 1987 publication-title: Biophys. J. – volume: 111 38 start-page: 402 389 year: 1999 1999 publication-title: Angew. Chem. Angew. Chem. Int. Ed. – volume: 22 start-page: 1937 year: 2006 publication-title: Langmuir – volume: 121 start-page: 81 year: 2003 publication-title: J. Gen. Physiol. – volume: 120 start-page: 267 year: 2002 publication-title: J. Gen. Physiol. – volume: 23 start-page: 2924 year: 2007 end-page: 2927 publication-title: Langmuir – volume: 86 start-page: 955 year: 2004 publication-title: Biophys. J. – volume: 1565 start-page: 287 year: 2002 publication-title: Biochim. Biophys. Acta Biomembr. – volume: 269 start-page: 676 year: 1994 publication-title: J. Biol. Chem. – volume: 261 start-page: 221 year: 1993 publication-title: Science – volume: 115 42 start-page: 219 208 year: 2003 2003 publication-title: Angew. Chem. Angew. Chem. Int. Ed. – volume: 82 start-page: 545 year: 2004 publication-title: Toxicol. Sci. – volume: 116 start-page: 75 year: 2000 publication-title: J. Gen. Physiol. – volume: 353 start-page: 846 year: 1991 publication-title: Nature – volume: 84 start-page: 1 year: 1984 publication-title: J. Gen. Physiol. – volume: 13 start-page: 112 year: 1998 publication-title: News Physiol. Sci. – volume: 91 start-page: 2163 year: 2006 publication-title: Biophys. J. – volume: 66 start-page: 996 year: 1994 publication-title: Biophys. J. – volume: 269 start-page: 676 year: 1994 ident: e_1_2_4_21_2 publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(17)42402-1 contributor: fullname: Garcia‐Calvo M. – ident: e_1_2_4_10_2 doi: 10.1016/S0005-2736(02)00575-8 – ident: e_1_2_4_23_2 doi: 10.1085/jgp.84.1.1 – ident: e_1_2_4_17_2 doi: 10.1021/la0342060 – volume: 13 start-page: 112 year: 1998 ident: e_1_2_4_11_2 publication-title: News Physiol. Sci. contributor: fullname: Toro L. – ident: e_1_2_4_4_2 doi: 10.1002/(SICI)1521-3757(19990201)111:3<402::AID-ANGE402>3.0.CO;2-D – ident: e_1_2_4_12_2 doi: 10.1085/jgp.20028721 – ident: e_1_2_4_1_2 doi: 10.1038/35093038 – ident: e_1_2_4_15_2 doi: 10.1073/pnas.85.22.8703 – ident: e_1_2_4_8_2 doi: 10.1021/la063503c – volume-title: Ion Channels of Excitable Membranes year: 2001 ident: e_1_2_4_9_2 contributor: fullname: Hille B. – ident: e_1_2_4_5_2 doi: 10.1021/la052534p – ident: e_1_2_4_7_2 doi: 10.1016/S0006-3495(04)74171-5 – ident: e_1_2_4_18_2 doi: 10.1002/ange.200390048 – ident: e_1_2_4_4_3 doi: 10.1002/(SICI)1521-3773(19990201)38:3<389::AID-ANIE389>3.0.CO;2-U – ident: e_1_2_4_19_2 doi: 10.1016/S0006-3495(87)83298-8 – ident: e_1_2_4_22_2 doi: 10.1085/jgp.116.1.75 – ident: e_1_2_4_14_2 doi: 10.1126/science.7687074 – ident: e_1_2_4_24_2 doi: 10.1016/S0006-3495(94)80883-5 – ident: e_1_2_4_25_2 doi: 10.1093/toxsci/kfh269 – ident: e_1_2_4_6_2 doi: 10.1529/biophysj.106.083592 – ident: e_1_2_4_18_3 doi: 10.1002/anie.200390080 – ident: e_1_2_4_20_2 doi: 10.1016/S0006-3495(94)80881-1 – ident: e_1_2_4_16_2 doi: 10.1038/353846a0 – ident: e_1_2_4_2_2 doi: 10.1021/la034197v – ident: e_1_2_4_3_2 doi: 10.1038/42432 – ident: e_1_2_4_13_2 doi: 10.1085/jgp.20028605 |
| SSID | ssj0009631 |
| Score | 2.1661055 |
| Snippet | The ties that bind. A biosensor based on modulation of single ion‐channel activity, with the ability to detect analytes in the micromolar range was devised.... |
| SourceID | proquest crossref pubmed wiley istex |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | 1246 |
| SubjectTerms | Biosensing Techniques - instrumentation Biosensing Techniques - methods Ion Channel Gating ion channels Ion Channels - metabolism Lipid Bilayers - chemistry lipids membranes Microarray Analysis Molecular Structure Probability single-molecule studies |
| Title | Functional Ion Channels in Tethered Bilayer Membranes-Implications for Biosensors |
| URI | https://api.istex.fr/ark:/67375/WNG-8Z5RRS8Z-8/fulltext.pdf https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fcbic.200700094 https://www.ncbi.nlm.nih.gov/pubmed/17583881 https://search.proquest.com/docview/70722819 |
| Volume | 8 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3NbtQwEB6hcigXCi3QQKE-oPaUdu3YsXNsF5YuUnvYtqLqxbITR1q1TdBmVwJOPARP2Cdh7DS7XVQJCS6RItnKZGY8nj9_BnhvuTJ5ybM4s1kZewSw2AqDD26MypjL0txXdI9P0qNz_vlCXNw7xd_iQ8wTbn5lBHvtF7ixzf4CNDS34xaCMHTHoRGmifQ9fR9GC_wo1K4QcXFf7mRMdqiNPba_PH1pV3rsGfztIZdz2YMNW9BgDUxHfNt5crU3m9q9_McfuI7_83fP4Omdf0oOWoV6Do9ctQ4bBxXG5jffyQ4JHaMhFb8Oq_3utrgNOB3gBtnmFcmwrog_tYA0NGRckbNwqNgV5HB8bdDFJ8fuBmlDI3v789fwXks7QQ8aB9UNxtb1pHkB54OPZ_2j-O7ChjjnXPKYctNjpUxKmyoraGIztBcpy62lOSsMzx2lKSup5bRwTBUKwzMMf5iRziSG2-QlrFR15TaBFKJwvEhFYYRH-HcG_UJGrUj8veWpNBHsdgLTX1tcDt0iMDPteafnvItgJ8hzPsxMrnw3mxT6y8knrS7FaHSqLrWKYLsTuEbm-cIJcqKeNVr2JPMFxwhetXqw-KT0ZWdFI2BBmn-hRfcPh_352-t_mfQGnnTpZZZswcp0MnNv0S-a2ndB938DIfYDsQ |
| link.rule.ids | 314,780,784,1375,27924,27925,46294,46718 |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwEB5BeygXHi2P8KoPqJzSrh07do7twrIL3T1stwL1YtmJI61KE7QPCTjxI_iF_BLGTrPLIiQkuESKZCuTGY89z88ALyxXJi95Fmc2K2OPABZbYfDBjVEZc1ma-4zucJT2z_nbD6KtJvS9MA0-xCrg5jUj7NdewX1A-miNGprbaYNBGMrjbsI26jz1VV2vxmsEKVxfwefiPuHJmGxxGzvsaHP-xrm07Vn8-U9G56YNGw6h3h2wLflN7cnl4XJhD_OvvyE7_tf_3YXb1yYqOW7W1D244apd2Duu0D2_-kIOSCgaDdH4XdjpthfG7cFZD8_IJrRIBnVFfOMCEjEn04pMQl-xK8jJ9KNBK58M3RUSh_vsj2_fB79UtRM0onFQPUf3up7N78N57_Wk24-v72yIc84ljyk3HVbKpLSpsoImNsMtI2W5tTRnheG5ozRlJbWcFo6pQqGHhh4QM9KZxHCbPICtqq7cIyCFKBwvUlEY4UH-nUHTkFErEn91eSpNBC9bielPDTSHbkCYmfa80yveRXAQBLoaZmaXvqBNCv1-9EarCzEen6kLrSLYbyWukXk-d4KcqJdzLTuS-ZxjBA-bhbD-pPSZZ0UjYEGcf6FFd08G3dXb43-ZtA87_cnwVJ8ORu-ewK022sySp7C1mC3dMzSTFvZ5UISfcREH0g |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwEB5BKwGXAi3Q8KoPqJzSrh07do7tlqULdIW2rah6sezEkValSbUPCTjxI_iF_BLGTrPbRUhIcIkUyVYmM3588_BngFeWK5OXPIszm5WxZwCLrTD44MaojLkszX1G92iQHp7yd2fi7MYp_oYfYh5w8zMjrNd-gl8V5e6CNDS3o4aCMFTH3YZVnrLMs-cfDBcEUji8gsvFfb6TMdnSNnbY7nL_pW1p1Wv4y58w5zKEDXtQ7z6YVvqm9ORiZza1O_m334gd_-f3HsDaNUAle82Iegi3XLUOG3sVOueXX8k2CSWjIRa_Dne77XVxG3Dcwx2yCSySfl0Rf2wBZZiQUUVOwqliV5D90WeDGJ8cuUuUDVfZn99_9G_UtBOE0NionqBzXY8nj-C09-akexhf39gQ55xLHlNuOqyUSWlTZQVNbIYLRspya2nOCsNzR2nKSmo5LRxThUL_DP0fZqQzieE2eQwrVV25TSCFKBwvUlEY4Sn-nUFgyKgVib-4PJUmgtetwfRVQ8yhGwpmpr3u9Fx3EWwHe86bmfGFL2eTQn8avNXqXAyHx-pcqwi2WoNrVJ7PnKAm6tlEy45kPuMYwZNmHCw-KX3eWdEIWLDmX2TR3f1-d_729F86bcGdjwc9_aE_eP8M7rWhZpY8h5XpeOZeIEaa2pdhGvwCTX8GgQ |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Functional+ion+channels+in+tethered+bilayer+membranes--implications+for+biosensors&rft.jtitle=Chembiochem+%3A+a+European+journal+of+chemical+biology&rft.au=Keizer%2C+Henk+M&rft.au=Dorvel%2C+Brian+R&rft.au=Andersson%2C+Martin&rft.au=Fine%2C+Daniel&rft.date=2007-07-23&rft.issn=1439-4227&rft.volume=8&rft.issue=11&rft.spage=1246&rft_id=info:doi/10.1002%2Fcbic.200700094&rft_id=info%3Apmid%2F17583881&rft.externalDocID=17583881 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1439-4227&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1439-4227&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1439-4227&client=summon |