Optimal introduction of laparoscopic liver resection for Child–Pugh B

• Published in: Asian journal of endoscopic surgery Vol. 12; no. 3; pp. 287 - 293
• Main Authors: Fuji, Hiroaki, Seo, Satoru, Toda, Rei, Yoh, Tomoaki, Ikeno, Yoshinobu, Fukumitsu, Ken, Ishii, Takamichi, Taura, Kojiro, Hatano, Etsuro, Kaido, Toshimi, Uemoto, Shinji
• Format: Journal Article
• Language: English
• Published: Kyoto, Japan John Wiley & Sons Australia, Ltd 01.07.2019; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; Aged, 80 and over; Carcinoma - mortality; Carcinoma - pathology; Carcinoma - surgery; Child–Pugh B; Female; Hepatectomy; Humans; laparoscopic liver resection; Laparoscopy; Length of Stay; Liver; Liver Neoplasms - mortality; Liver Neoplasms - pathology; Liver Neoplasms - surgery; Male; Middle Aged; Operative Time; Retrospective Studies; RFA; Survival Rate; Treatment Outcome; Young Adult; RFA; laparoscopic liver resection; Child-Pugh B
• ISSN: 1758-5902; 1758-5910
• DOI: 10.1111/ases.12634

Introduction Surgery for Child–Pugh B liver function is considered risky because of its high morbidity rate and the acceptable indication criteria for laparoscopic liver resection (LLR) for Child–Pugh B patients have not been identified. We conducted a retrospective cohort study to determine the optimal introduction of LLR for Child–Pugh B patients based on our single‐institute experience. Methods A total of 17 Child–Pugh B patients underwent LLR between 2005 and 2017. Their clinical outcomes were compared to those of LLR for Child–Pugh A patients (103 cases), conventional open liver resection for Child–Pugh B patients (19 cases), and radiofrequency ablation (RFA) for Child–Pugh B patients (20 cases) during the same period. Results LLR for Child–Pugh B patients had a significantly higher conversion rate than LLR for Child–Pugh A patients (Child–Pugh A vs B: 3.9% vs 35.3%, P < 0.01). However, patients who successfully underwent laparoscopic resection (11 cases) had fewer postoperative ascites and shorter postoperative hospital stays compared to patients who underwent conventional open liver resection. In comparison to the RFA group, the LLR group more frequently had lesions in the left lateral segment (LLR vs RFA: 50.0% vs 10.0%, P = 0.02) and exophytic tumor (21.4% vs 0%, P = 0.02) than did the RFA group. Also, compared to the RFA group, the LLR group had a lower local recurrence rate (0% vs 15%, P = 0.25) and a longer recurrence‐free survival (P = 0.049), but the overall survival was similar between the two groups. Conclusions In the treatment of Child–Pugh B liver malignancy, the minimal invasiveness of LLR was revealed. Our results suggest that lesions in the left lateral segment and exophytic tumors are good indications for LLR for Child–Pugh B.