Prevalence and determinants of diabetes and impaired fasting glucose among urban community-dwelling adults in Guangzhou, China

• Published in: Diabetes & metabolism Vol. 35; no. 5; pp. 378 - 384
• Main Authors: Wang, H, Qiu, Q, Tan, L.-L, Liu, T, Deng, X.-Q, Chen, Y.-M, Chen, W, Yu, X.-Q, Hu, B.-J, Chen, W.-Q
• Format: Journal Article
• Language: English
• Published: Paris Elsevier Masson SAS 01.11.2009; Masson
• Subjects: Adult; Adulte; Aged; Aged, 80 and over; Aging; Associated factors; Biological and medical sciences; China; China - epidemiology; Chine; Diabetes Complications; Diabetes mellitus; Diabetes Mellitus - diagnosis; Diabetes Mellitus - epidemiology; Diabetes Mellitus - prevention & control; Diabetes. Impaired glucose tolerance; Diabète sucré; Dépistage; Endocrine pancreas. Apud cells (diseases); Endocrinology & Metabolism; Endocrinopathies; Epidemiology; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Facteurs associés; Female; Genetic Predisposition to Disease; Glucose Intolerance - epidemiology; Health Surveys; Humans; Hyperglycémie modérée à jeun; Hyperlipidemias - complications; Hyperlipidemias - epidemiology; Hypertension - complications; Hypertension - epidemiology; Impaired fasting glucose; Internal Medicine; Male; Medical sciences; Middle Aged; Obesity - complications; Obesity - epidemiology; Overweight - complications; Overweight - epidemiology; Prevalence; Risk Factors; Screening; Sex Factors; Urbain; Urban; Urban Population; Young Adult; Épidémiologie; Asia; China; Urbain; Impaired fasting glucose; Diabetes mellitus; Adulte; Épidémiologie; Hyperglycémie modérée à jeun; Epidemiology; Dépistage; Urban; Associated factors; Screening; Diabète sucré; China; Adult; Chine; Facteurs associés; Endocrinopathy; Hyperglycemia; Fasting; Prevalence; Glucose; Medical screening
• ISSN: 1262-3636; 1878-1780
• DOI: 10.1016/j.diabet.2009.03.006

Abstract Aim This study aimed to estimate the prevalence of diabetes and impaired fasting glucose (IFG) in the adult population aged ≥ 20 years in Guangzhou and to evaluate the associated risk factors. Method A total of 6197 randomly selected adults, aged ≥ 20 years and living for at least 5 years in Guangzhou, participated in questionnaire-based interviews between 2006 and 2007, and had their clinical characteristics and standard blood chemistries measured. A 75 g OGTT was conducted for those subjects with fasting glucose levels ≥ 5.6 mmol/L. Diabetes and IFG were defined according to WHO 1999 criteria. Results Based on Chinese census data, the age- and gender-standardized prevalences of diabetes and IFG were 5.5% and 3.3%, respectively. Among the identified diabetic individuals in the present investigation, 42.3% were newly diagnosed. The prevalence of diabetes and IFG increased with age. The results of multivariate logistic-regression analyses showed that diabetes and IFG were significantly associated with age, a family history of diabetes, obesity, hypertension and hyperlipidaemia. Conclusion The prevalences of diabetes and IFG have increased dramatically over the past decade. Yet, a large proportion of cases go undiagnosed. These results suggest an urgent need to establish regular population-based diabetes screening in Guangzhou.