Anticonvulsant effects of ivermectin in genetically-epileptic chickens
In genetically-photosensitive epileptic chickens, the anti-parasitic agent ivermectin, at 1.0 and 5.0 mg/kg, decreased or prevented seizures induced by intermittent photic stimulation without any side-effects on the central nervous system. The latency and duration of this anti-convulsant effect was...
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Published in | Neuropharmacology Vol. 25; no. 10; p. 1085 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
England
01.10.1986
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Subjects | |
Online Access | Get more information |
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Summary: | In genetically-photosensitive epileptic chickens, the anti-parasitic agent ivermectin, at 1.0 and 5.0 mg/kg, decreased or prevented seizures induced by intermittent photic stimulation without any side-effects on the central nervous system. The latency and duration of this anti-convulsant effect was dose-dependent. When combined with diazepam, ivermectin prolonged the anti-convulsant action of diazepam. |
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ISSN: | 0028-3908 |
DOI: | 10.1016/0028-3908(86)90154-1 |