Moderate hypothermia technique for chronic implantation of a total artificial heart in calves

The benefit of whole-body hypothermia in preventing ischemic injury during cardiac surgical operations is well documented. However, application of hypothermia during in vivo total artificial heart implantation has not become widespread because of limited understanding of the proper techniques and re...

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Bibliographic Details
Published inJournal of artificial organs Vol. 20; no. 2; pp. 182 - 185
Main Authors Karimov, Jamshid H., Grady, Patrick, Sinkewich, Martin, Sunagawa, Gengo, Dessoffy, Raymond, Byram, Nicole, Moazami, Nader, Fukamachi, Kiyotaka
Format Journal Article
LanguageEnglish
Published Tokyo Springer Japan 01.06.2017
Springer Nature B.V
Subjects
Animals
Artificial organs
Biomedical Engineering and Bioengineering
Brief Communication
Calves
Cardiac Surgery
Cardiac Surgical Procedures
Cattle
Heart
Heart diseases
Heart implantation
Heart, Artificial
Hypothermia
Hypothermia, Induced - methods
Implantation
Injury prevention
Inventions
Ischemia
Medicine
Medicine & Public Health
Models, Animal
Nephrology
Surgery
Surgical implants
Assisted circulation
Heart-assist devices
Experimental surgery
Hypothermia
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Summary:The benefit of whole-body hypothermia in preventing ischemic injury during cardiac surgical operations is well documented. However, application of hypothermia during in vivo total artificial heart implantation has not become widespread because of limited understanding of the proper techniques and restrictions implied by constitutional and physiological characteristics specific to each animal model. Similarly, the literature on hypothermic set-up in total artificial heart implantation has also been limited. Herein we present our experience using hypothermia in bovine models implanted with the Cleveland Clinic continuous-flow total artificial heart.
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ISSN:1434-7229
1619-0904
DOI:10.1007/s10047-017-0946-9