Malignant extrapleural solitary fibrous tumor arising in the sublingual gland: A case report and review of literature

Solitary fibrous tumor is an uncommon neoplasm with unpredictable clinical behavior. Malignant solitary fibrous tumor is a rare morphological variant with more aggressive behavior and higher rates of local recurrences and distant metastasis, exceeding rare in oral cavity; our case occurred in the fl...

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Published inOral oncology Vol. 90; pp. 141 - 144
Main Authors Iorio, Brigida, Ronchi, Andrea, Montella, Marco, Cozzolino, Immacolata, De Luca, Roberto, Rusciano, Mario, Tartaro, Gianpaolo, Colella, Giuseppe, Franco, Renato
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.03.2019
Subjects
12E7 Antigen - metabolism
Adult
Aldehyde Dehydrogenase 1 - metabolism
ALDH1
Antigens, CD34 - metabolism
Female
Head and neck neoplasm
Humans
Immunohistochemistry
Malignant extrapleural solitary fibrous tumor
Margins of Excision
Oral cavity neoplasm
Proto-Oncogene Proteins c-bcl-2 - metabolism
Retinal Dehydrogenase - metabolism
Solitary Fibrous Tumors - diagnosis
Solitary Fibrous Tumors - surgery
STAT6
Sublingual Gland Neoplasms - diagnosis
Sublingual Gland Neoplasms - surgery
Treatment Outcome
STAT6
Head and neck neoplasm
Oral cavity neoplasm
ALDH1
Malignant extrapleural solitary fibrous tumor
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Summary:Solitary fibrous tumor is an uncommon neoplasm with unpredictable clinical behavior. Malignant solitary fibrous tumor is a rare morphological variant with more aggressive behavior and higher rates of local recurrences and distant metastasis, exceeding rare in oral cavity; our case occurred in the floor of the mouth in the sublingual gland.
Bibliography:SourceType-Scholarly Journals-1
ObjectType-Correspondence-1
content type line 23
ObjectType-Report-3
ObjectType-Review-2
ObjectType-Case Study-4
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2018.12.013