Fatal anaphylactic reaction to diclofenac

A case of apparent anaphylactic reaction to diclofenac sodium (Voltaren) is reported. A 45-year-old man collapsed 15 min after intramuscular injection of diclofenac for treatment of low back pain. Twenty minutes following successful resuscitation, he went into coma from which he never recovered and...

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Bibliographic Details
Published inForensic science international Vol. 60; no. 1; pp. 107 - 110
Main Authors Alkhawajah, A.M., Eifawal, M., Mahmoud, S.F.
Format Journal Article
LanguageEnglish
Published Kidlington Elsevier Ireland Ltd 01.06.1993
Elsevier
Subjects
Anaphylaxis
Anaphylaxis - etiology
Anaphylaxis - pathology
Biological and medical sciences
Diclofenac
Diclofenac - adverse effects
Drug Hypersensitivity - etiology
Drug Hypersensitivity - pathology
Drug toxicity and drugs side effects treatment
Humans
Hypersensitivity
Low Back Pain - drug therapy
Male
Medical sciences
Middle Aged
Miscellaneous (drug allergy, mutagens, teratogens...)
Non-steroidal anti-inflammatory drugs
Pharmacology. Drug treatments
Anaphylaxis
Hypersensitivity
Diclofenac
Non-steroidal anti-inflammatory drugs
Non steroidal antiinflammatory agent
Case study
Human
Allergy
Immunopathology
Legal medicine
Toxicity
Death
Male
Intramuscular administration
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Summary:A case of apparent anaphylactic reaction to diclofenac sodium (Voltaren) is reported. A 45-year-old man collapsed 15 min after intramuscular injection of diclofenac for treatment of low back pain. Twenty minutes following successful resuscitation, he went into coma from which he never recovered and was pronounced dead on the following day. To our knowledge, this is the first reported case of anaphylactic reaction to diclofenac.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0379-0738
1872-6283
DOI:10.1016/0379-0738(93)90098-U