Does high maternal first trimester iron status have an effect on the 50 g oral glucose test?

• Published in: Journal of obstetrics and gynaecology Vol. 32; no. 4; p. 332
• Main Authors: Yeniel, A Ö, Ergenoglu, A M, Sanhal, C Y, Sahin, C, Ulukus, M, Oztekin, K
• Format: Journal Article
• Language: English
• Published: England 01.05.2012
• Subjects: Blood Glucose - metabolism; Diabetes, Gestational - blood; Diabetes, Gestational - diagnosis; Female; Ferritins - blood; Glucose Tolerance Test; Humans; Iron - blood; Iron - metabolism; Pregnancy; Pregnancy Trimester, First
• ISSN: 1364-6893
• DOI: 10.3109/01443615.2012.658894

We aimed to test the hypothesis that 1st trimester high body iron status is associated with a high positive 50 g oral glucose tolerance test. In this study, 29 pregnant women with positive 50 g oral glucose tolerance test were compared with 94 negative 50 g OGTT patients as the control group in terms of 1st trimester iron status. Both groups had similar age, weight, height, body mass index and also median gravidity and parity values. Our results showed that there were no differences between groups in mean haemoglobin, haematocrit, serum iron, serum ferritin, total iron binding capacity and transferrin. Since it seems that free radicals have much influence on oxidative stress and glucose metabolism, prospective, randomised clinical trials should be designed to demonstrate the possible relation between maternal iron status and glucose intolerance.