Therapeutic mechanisms of ginseng in coronary heart disease

Coronary heart disease (CHD) is the most common clinical manifestation of cardiovascular disease. It is characterized by myocardial ischemia, which is caused by coronary atherosclerosis. CHD is a significant global health problem with increasing prevalence every year because of significant changes i...

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Published inFrontiers in pharmacology Vol. 14; p. 1271029
Main Authors Tang, Miao-Miao, Zhao, Shu-Ting, Li, Ran-Qi, Hou, Wei
Format Journal Article
LanguageEnglish
Published Frontiers Media S.A 03.10.2023
Subjects
antioxidation
atherosclerosis
blood pressure
coronary heart disease (CHD)
ginseng
heart
Pharmacology
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Summary:Coronary heart disease (CHD) is the most common clinical manifestation of cardiovascular disease. It is characterized by myocardial ischemia, which is caused by coronary atherosclerosis. CHD is a significant global health problem with increasing prevalence every year because of significant changes in the lifestyles and diets. Ginseng is a traditional Chinese medicinal herb that has been used in food preparations and traditional medicine for several centuries. Several studies have demonstrated that ginseng improved cardiac function by normalizing blood glucose levels and decreasing blood pressure, oxidative stress, platelet aggregation, and lipid dysregulation in vivo . This review describes the current understanding of the mechanisms by which ginseng alleviates CHD, and provides a reference for the clinical development and application of ginseng as an alternative therapy for CHD.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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Reviewed by: Syed Anees Ahmed, East Carolina University, United States
Edited by: Adolfo Andrade-Cetto, National Autonomous University of Mexico, Mexico
ISSN:1663-9812
1663-9812
DOI:10.3389/fphar.2023.1271029