Neuroendoscopic surgery in neonates — indication and results over a 10-year practice

• Published in: Child's nervous system Vol. 37; no. 11; pp. 3541 - 3548
• Main Authors: Schaumann, Andreas, Bührer, Christoph, Schulz, Matthias, Thomale, Ulrich-Wilhelm
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2021
• Subjects: Annual Issue Paper; Cerebral Hemorrhage - surgery; Child; Child, Preschool; Humans; Hydrocephalus - surgery; Infant; Infant, Newborn; Medicine; Medicine & Public Health; Neuroendoscopes; Neuroendoscopy; Neurosciences; Neurosurgery; Retrospective Studies; Treatment Outcome; Neonates; Ventricle peritoneal shunt; Neuroendoscopic lavage; Posthemorrhagic hydrocephalus; Intraventricular hemorrhage; Neuroendoscopy; Intraventricular infection; Postinfectious hydrocephalus
• ISSN: 0256-7040; 1433-0350
• DOI: 10.1007/s00381-021-05272-y

Purpose Neuroendoscopic procedures for treatment of term and preterm newborn infants, such as endoscopic lavage for posthemorrhagic hydrocephalus, are gaining popularity despite sparse data. This single-institution report compiles all neuroendoscopic surgical procedures performed in neonates during a 10-year period. Methods Charts and electronic records were reviewed of all consecutive newborns who underwent a neuroendoscopic procedure before reaching a postmenstrual age of 44 weeks between 09/2010 and 09/2020. Available documentation was reviewed regarding the performed neuroendoscopic procedure, course of disease, complications, and all re-operations throughout the first year of life. Results During the 10-year study period, 116 infants (median gestational age at birth: 29 1 /7 weeks) underwent a total of 153 neuroendoscopic procedures (median postmenstrual age at surgery: 35 0 /7 weeks). The most common indication at the time of the neuroendoscopic procedures (n = 153) was intraventricular hemorrhage (IVH, n = 119), intraventricular infection (n = 15), congenital malformation (n = 8), isolated 4th ventricle (n = 7), multiloculated hydrocephalus (n = 3), and tumor (n = 1). Thirty-eight of 116 children (32.8%) underwent 43 operative revisions after 153 neuroendoscopic procedure (28.1%). Observed complications requiring surgical revision were secondary infection (n = 11), CSF fistula (n = 9), shunt dysfunction (n = 8), failure of ETV (n = 6), among others. 72 children (62%) of 116 children required permanent CSF diversion via a shunt. The respective shunt rates per diagnosis were 47 of 80 (58.8%) for previously untreated IVH, 11 of 13 (84.6%) for intraventricular infection. Shunt survival rate for the first year of life was 74% for the whole cohort. Conclusion The experience with this large cohort of neonates demonstrates the feasibility of neuroendoscopic technique for the treatment of posthemorrhagic or postinfectious hydrocephalus. Rate and type of complications after neuroendoscopic procedures were within the expected range. Assessing the potential long-term benefits of neuroendoscopic techniques has to await results of ongoing studies.