Two new sesquiterpenes from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activities

Two new sesquiterpenes, nicotianasesterpenes A and B (1 and 2), together with five known sesquiterpenes (3-7) were isolated from the leaves of Nicotiana tabacum. Their structures were determined mainly by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. The anti-tobacco mosaic v...

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Published inNatural product research Vol. 30; no. 22; pp. 2545 - 2550
Main Authors Shen, Qinpeng, Xu, Xingmeng, Liu, Chunbo, Zhao, Wei, Xiang, Nengjun, Chen, Yongkuan, Miao, Mingming, Liu, Zhihua, Yang, Guangyu
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 16.11.2016
Subjects
anti-tobacco mosaic virus activity
Nicotiana tabacum
sesquiterpenes
Nicotiana tabacum
anti-tobacco mosaic virus activity
sesquiterpenes
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Summary:Two new sesquiterpenes, nicotianasesterpenes A and B (1 and 2), together with five known sesquiterpenes (3-7) were isolated from the leaves of Nicotiana tabacum. Their structures were determined mainly by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. The anti-tobacco mosaic virus (anti-TMV) activities of compounds 1-7 were evaluated. The results revealed that compound 1 exhibited high anti-TMV activities with inhibition rates of 33.6%. This rate is high than that of positive control. The other compounds also showed potential activities with inhibition rates in the range of 18.8-28.4%, respectively. The structures of compounds 1-2.
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ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2015.1120729