Deep-probe metal-clad waveguide biosensors
Two types of metal-clad waveguide biosensors, so-called dip-type and peak-type, are analyzed and tested. Their performances are benchmarked against the well-known surface-plasmon resonance biosensor, showing improved probe characteristics for adlayer thicknesses above 150–200nm. The dip-type metal-c...
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Published in | Biosensors & bioelectronics Vol. 22; no. 7; pp. 1282 - 1288 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Lausanne
Elsevier B.V
15.02.2007
Elsevier Science |
Subjects | |
Online Access | Get full text |
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Summary: | Two types of metal-clad waveguide biosensors, so-called dip-type and peak-type, are analyzed and tested. Their performances are benchmarked against the well-known surface-plasmon resonance biosensor, showing improved probe characteristics for adlayer thicknesses above 150–200nm. The dip-type metal-clad waveguide sensor is shown to be the best all-round alternative to the surface-plasmon resonance biosensor. Both metal-clad waveguides are tested experimentally for cell detection, showing a detection limit of 8–9cells/mm2. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-3 ObjectType-Review-1 |
ISSN: | 0956-5663 1873-4235 |
DOI: | 10.1016/j.bios.2006.05.025 |