Evaluation of obstetric outcomes and prognostic significance of graft function in kidney transplant recipient pregnancies

To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation. We retrospectively reviewed 32 singleton pregnancies in kidney transplant recipients. Obstetric outcomes were explored according to the estimated glomerular filtration rates (eGFR) of patients. The incidences of fe...

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Published inHypertension in pregnancy Vol. 39; no. 2; pp. 89 - 94
Main Authors Madazlı, Riza, Kaymak, Didem, Alpay, Verda, Erenel, Hakan, Dincer, M. Tamer, Seyahi, Nurhan
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 02.04.2020
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Abstract To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation. We retrospectively reviewed 32 singleton pregnancies in kidney transplant recipients. Obstetric outcomes were explored according to the estimated glomerular filtration rates (eGFR) of patients. The incidences of fetal growth restriction, preeclampsia were 18.8% and 34.4%, respectively. There was a significant negative correlation between first-trimester eGFR and perinatal mortality (r = −0.546, p = .0.001) and composite adverse obstetric outcome (r = −0.415, p = .0.018). The degree of transplanted kidney function impairment at the beginning of pregnancy is the major determinant of pregnancy outcome.
AbstractList Objective To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation. Methods We retrospectively reviewed 32 singleton pregnancies in kidney transplant recipients. Obstetric outcomes were explored according to the estimated glomerular filtration rates (eGFR) of patients. Results The incidences of fetal growth restriction, preeclampsia were 18.8% and 34.4%, respectively. There was a significant negative correlation between first-trimester eGFR and perinatal mortality (r = −0.546, p = .0.001) and composite adverse obstetric outcome (r = −0.415, p = .0.018). Conclusion The degree of transplanted kidney function impairment at the beginning of pregnancy is the major determinant of pregnancy outcome.
To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation. We retrospectively reviewed 32 singleton pregnancies in kidney transplant recipients. Obstetric outcomes were explored according to the estimated glomerular filtration rates (eGFR) of patients. The incidences of fetal growth restriction, preeclampsia were 18.8% and 34.4%, respectively. There was a significant negative correlation between first-trimester eGFR and perinatal mortality (r = −0.546, p = .0.001) and composite adverse obstetric outcome (r = −0.415, p = .0.018). The degree of transplanted kidney function impairment at the beginning of pregnancy is the major determinant of pregnancy outcome.
: To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation. : We retrospectively reviewed 32 singleton pregnancies in kidney transplant recipients. Obstetric outcomes were explored according to the estimated glomerular filtration rates (eGFR) of patients. : The incidences of fetal growth restriction, preeclampsia were 18.8% and 34.4%, respectively. There was a significant negative correlation between first-trimester eGFR and perinatal mortality (r = -0.546, p = .0.001) and composite adverse obstetric outcome (r = -0.415, p = .0.018). : The degree of transplanted kidney function impairment at the beginning of pregnancy is the major determinant of pregnancy outcome.
Author Madazlı, Riza
Seyahi, Nurhan
Alpay, Verda
Erenel, Hakan
Dincer, M. Tamer
Kaymak, Didem
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obstetric outcomes
glomerular filtration rate
pregnancy
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: To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation. : We retrospectively reviewed 32 singleton pregnancies in kidney...
Objective To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation. Methods We retrospectively reviewed 32 singleton pregnancies in...
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SubjectTerms Adult
Female
Fetal Growth Retardation - epidemiology
Fetal Growth Retardation - physiopathology
glomerular filtration rate
Glomerular Filtration Rate - physiology
Humans
Incidence
Kidney - physiopathology
Kidney transplant
Kidney Transplantation
obstetric outcomes
Pre-Eclampsia - epidemiology
Pre-Eclampsia - physiopathology
Pregnancy
Pregnancy Outcome
Prognosis
Retrospective Studies
Transplant Recipients
Title Evaluation of obstetric outcomes and prognostic significance of graft function in kidney transplant recipient pregnancies
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