Association of Cheyne–Stokes respiration and cardiac cachexia in congestive heart failure

Abstract In patients with congestive heart failure (CHF) cachexia as well as Cheyne–Stokes respiration (CSR) are well known disorders. The relationship between CSR and cardiac cachexia however, remains unclear so far. Clinical as well as full-night polysomnographic data from 12 cachectic patients we...

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Published inInternational journal of cardiology Vol. 142; no. 3; pp. 298 - 300
Main Authors Hagenah, Gerrit C, Luers, Claus, Prager, Denise, Blaschke, Sabine
Format Journal Article
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 23.07.2010
Elsevier
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Summary:Abstract In patients with congestive heart failure (CHF) cachexia as well as Cheyne–Stokes respiration (CSR) are well known disorders. The relationship between CSR and cardiac cachexia however, remains unclear so far. Clinical as well as full-night polysomnographic data from 12 cachectic patients were compared to 13 non-cachectic patients with CHF. The non-cachectic patients did not differ significantly in age (57.3 ± 11.6 vs 64.8 ± 14.5 years), body mass index (26.4 ± 4.0 vs 25.2 ± 3.2 kg mˉ 2 ) or ejection fraction (21.8 ± 5 vs 23.3 ± 7%) from cachectic patients. The weight loss was 2.1 ± 2.3 kg in non-cachectic vs 11.5 ± 2.7 kg in cachectic patients ( p < 0.0001). A significant difference was detected for the prevalence CSR (5 vs 10 patients, p < 0.03). In this study a high prevalence of sleep breathing disorders, in particular of CSR in CHF patients with cachexia was detected.
Bibliography:SourceType-Other Sources-1
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ObjectType-Correspondence-1
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2008.11.118