Simplifying therapy to assure glycemic control and engagement (STAGE) in poorly-controlled diabetes: A pilot study

In this single-arm pilot study, we demonstrated feasibility and acceptability of an insulin simplification intervention in patients with persistent, poorly-controlled type 2 diabetes on complex insulin regimens. While not powered to assess clinical outcomes, we observed neither worsened glycemic con...

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Bibliographic Details
Published inJournal of diabetes and its complications Vol. 37; no. 1; p. 108364
Main Authors Alexopoulos, Anastasia-Stefania, Soliman, Diana, Lewinski, Allison A., Strawbridge, Elizabeth, Steinhauser, Karen, Edelman, David, Crowley, Matthew J.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.01.2023
Elsevier Limited
Subjects
Blood Glucose
Diabetes
Diabetes mellitus
Diabetes Mellitus, Type 1 - therapy
Diabetes Mellitus, Type 2 - drug therapy
Foot diseases
Funding
Glucose
Glycemic Control
Humans
Hyperglycemia
Hypoglycemia
Hypoglycemic Agents - adverse effects
Insulin
Insulin - adverse effects
Older people
Pilot Projects
Quality of life
R&D
Research & development
Simplification
Veterans
Insulin
Diabetes mellitus
Simplification
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Summary:In this single-arm pilot study, we demonstrated feasibility and acceptability of an insulin simplification intervention in patients with persistent, poorly-controlled type 2 diabetes on complex insulin regimens. While not powered to assess clinical outcomes, we observed neither worsened glycemic control nor increased hypoglycemia. •Insulin simplification is rarely studied outside of the context of older adult care.•Patients that maintain poor glucose control on complex insulin therapy can benefit.•Simplification in this population is feasible, acceptable and may improve HbA1c.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1056-8727
1873-460X
DOI:10.1016/j.jdiacomp.2022.108364