Validation of the Polish version of the EORTC QLQ-OV28 module for the assessment of health-related quality of life in women with ovarian cancer

• Published in: Expert review of pharmacoeconomics & outcomes research Vol. 14; no. 1; pp. 157 - 163
• Main Authors: Paradowski, Jan, Tomaszewski, Krzysztof A, Bereza, Krzysztof, Tomaszewska, Iwona M, Pasternak, Artur, Paradowska, Dominika, Szcz sny, Ewa, Golec, Edward B, Greimel, Elfriede R, Bottomley, Andrew
• Format: Journal Article
• Language: English
• Published: England Informa UK, Ltd 01.02.2014; Taylor & Francis; Informa Healthcare
• Subjects: Aged; Chemotherapy; Consent; cultural adaptation; EORTC; Female; Guidelines as Topic; Humans; Mann-Whitney U test; Medical prognosis; Middle Aged; Ovarian cancer; Ovarian Neoplasms - pathology; Patients; Pilot Projects; Poland; Prospective Studies; Quality of Life; Quality standards; Quantitative psychology; Questionnaires; Reproducibility of Results; Statistical analysis; Surveys and Questionnaires; validation; Validity; Womens health; Poland
• ISSN: 1473-7167; 1744-8379
• DOI: 10.1586/14737167.2014.868309

The aim of our study was to undertake a prospective validation study of the Polish version of the EORTC ovarian cancer (EORTC QLQ-OV28) module used together with the EORTC QLQ-C30. The translated module was pilot-tested according to the EORTC guidelines. Patients with histological confirmation of ovarian cancer were eligible for the study. All patients filled out the Polish version of the EORTC QLQ-OV28, the EORTC QLQ-C30 and a demographic questionnaire. Standard validity and reliability analyses were performed. One-hundred and forty patients agreed to take part in the study (mean age ± standard deviation: 63.3 ± 10.2 years). Cronbach's alpha coefficients showed positive internal consistency (0.78-0.91). Interclass correlations for the EORTC QLQ-OV28 ranged from 0.77 to 0.93 and proved appropriate test-retest reliability. Satisfactory convergent and discriminant validity in multi-trait scaling analyses was seen. The Polish version of the EORTC QLQ-OV28 module proved to be a reliable and valid tool for measuring health-related quality of life in patients with ovarian cancer.