Cherenkov Luminescence in Tumor Diagnosis and Treatment: A Review

Malignant tumors rank as a leading cause of death worldwide. Accurate diagnosis and advanced treatment options are crucial to win battle against tumors. In recent years, Cherenkov luminescence (CL) has shown its technical advantages and clinical transformation potential in many important fields, par...

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Bibliographic Details
Published inPhotonics Vol. 9; no. 6; p. 390
Main Authors Wang, Xianliang, Li, Lintao, Li, Jie, Wang, Pei, Lang, Jinyi, Yang, Yuanjie
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 31.05.2022
Subjects
Atoms & subatomic particles
Cancer
Cancer therapies
Care and treatment
Charged particles
Cherenkov luminescence
Cost analysis
Diagnosis
Diagnostic imaging
Endoscopes
Energy
Gene expression
Imaging techniques
Light
Luminescence
Medical diagnosis
Medical imaging
Medical research
Methods
molecular imaging
Nanoparticles
Photodynamic therapy
Physiology
Quantum dots
Radiation therapy
Reviews
Spectrum allocation
Tissues
tumor diagnosis
Tumor microenvironment
tumor treatment
Tumors
Velocity
China
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Summary:Malignant tumors rank as a leading cause of death worldwide. Accurate diagnosis and advanced treatment options are crucial to win battle against tumors. In recent years, Cherenkov luminescence (CL) has shown its technical advantages and clinical transformation potential in many important fields, particularly in tumor diagnosis and treatment, such as tumor detection in vivo, surgical navigation, radiotherapy, photodynamic therapy, and the evaluation of therapeutic effect. In this review, we summarize the advances in CL for tumor diagnosis and treatment. We first describe the physical principles of CL and discuss the imaging techniques used in tumor diagnosis, including CL imaging, CL endoscope, and CL tomography. Then we present a broad overview of the current status of surgical resection, radiotherapy, photodynamic therapy, and tumor microenvironment monitoring using CL. Finally, we shed light on the challenges and possible solutions for tumor diagnosis and therapy using CL.
ISSN:2304-6732
2304-6732
DOI:10.3390/photonics9060390