Exposure to Asbestos and Increased Intrahepatic Cholangiocarcinoma Risk: Growing Evidences of a Putative Causal Link

To date the true global incidence of intrahepatic cholangiocarcinoma (iCCA) and the underlying risk factors remain to be fully defined, in particular, the role of occupational and environmental factors. Currently, the putative role of asbestos exposure as a risk factor for iCCA is gaining increased...

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Bibliographic Details
Published inAnnals of global health Vol. 88; no. 1; p. 41
Main Authors Brandi, Giovanni, Straif, Kurt, Mandrioli, Daniele, Curti, Stefania, Mattioli, Stefano, Tavolari, Simona
Format Journal Article
LanguageEnglish
Published Amsterdam Ubiquity Press 01.01.2022
Subjects
Asbestos
Bile ducts
Cholangiocarcinoma
Cholangitis
Cysts
Disease
Environmental factors
Environmental risk
Epidemiology
Exposure
Infections
Inflammation
intrahepatic cholangiocarcimona
Letters to the Editor
Liver cancer
Lung cancer
Mesothelioma
Metastasis
Mutation
Occupational exposure
Patients
Risk factors
United States > US
Italy
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Summary:To date the true global incidence of intrahepatic cholangiocarcinoma (iCCA) and the underlying risk factors remain to be fully defined, in particular, the role of occupational and environmental factors. Currently, the putative role of asbestos exposure as a risk factor for iCCA is gaining increased attention in the international scientific community and agencies.In this commentary we review and integrate available epidemiological and mechanistic evidences that support a potential role of asbestos exposure in iCCA etiology.
Bibliography:SourceType-Scholarly Journals-1
ObjectType-Correspondence-2
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ObjectType-Review-1
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ISSN:2214-9996
2214-9996
DOI:10.5334/aogh.3660