Prolongation of the tibialis anterior CMAP duration in chronic inflammatory demyelinating polyneuropathy

• Published in: Clinical neurophysiology Vol. 123; no. 2; pp. 393 - 398
• Main Authors: Nodera, Hiroyuki, Latov, Norman, Carey, Bridget, Langsdorf, Jennifer, Bedoya, Veronica, Tacheva, Svetla, Chin, Russell L
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ireland Ltd 01.02.2012; Elsevier
• Subjects: Action Potentials - physiology; Adult; Aged; Aged, 80 and over; Biological and medical sciences; CIDP; Compound muscle action potential; Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction; Demyelination; Duration; Electrodiagnosis. Electric activity recording; Female; Humans; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Middle Aged; Muscle Contraction - physiology; Muscle, Skeletal - physiology; Nervous system; Nervous system (semeiology, syndromes); Neurology; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - diagnosis; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - physiopathology; Prospective Studies; Retrospective Studies; Tibialis anterior; Time Factors; Young Adult; chronic inflammatory demyelinating polyneuropathy; peroneal motor conduction study with recording from TA; EDB; extensor digitorum brevis; CMAP; AH; Duration; TA study; abductor hallucis; CIDP; TA; tibialis anterior; compound muscle action potential; distal compound muscle action potential; Demyelination; dCMAP; Compound muscle action potential; Tibialis anterior; Human; Electrophysiology; Axon; Action potential; Chronic inflammatory demyelinating neuropathy; Abductor hallucis muscle; Extensor digiti brevis muscle; Electrodiagnosis; Sensitivity
• ISSN: 1388-2457; 1872-8952
• DOI: 10.1016/j.clinph.2011.05.031

Highlights ► The normal duration of dCMAP recording from TA was determined to be 14 ms. ► The prolonged dCMAP duration from TA is a useful feature in diagnosing CIDP. ► Coexisting axon loss may mask demyelinating features in distal NCS studies.