After CAPRISA 004: time to re-evaluate the HIV lexicon

[...] they limit a more integrated approach to combination prevention of HIV infection. In 2008, we had suggested a new lexicon to categorise HIV-prevention interventions.6 As we have seen with CAPRISA 004, use of antiretrovirals to prevent HIV transmission has become a broad field of its own, encom...

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Bibliographic Details
Published inThe Lancet (British edition) Vol. 376; no. 9740; pp. 495 - 496
Main Author Cates, Willard
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 14.08.2010
Elsevier Limited
Subjects
Adenine - administration & dosage
Adenine - analogs & derivatives
Administration, Intravaginal
Administration, Oral
Anti-HIV Agents - administration & dosage
Antiretroviral agents
Female
Gels
HIV
HIV Infections - prevention & control
Human immunodeficiency virus
Humans
Integrated approach
Internal Medicine
Meetings
Organophosphonates - administration & dosage
Prevention
Prophylaxis
Randomized Controlled Trials as Topic
Reverse Transcriptase Inhibitors - administration & dosage
Risk taking
Tenofovir
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Summary:[...] they limit a more integrated approach to combination prevention of HIV infection. In 2008, we had suggested a new lexicon to categorise HIV-prevention interventions.6 As we have seen with CAPRISA 004, use of antiretrovirals to prevent HIV transmission has become a broad field of its own, encompassing many overlapping scientific issues.7 As with hormonal contraception as a method to prevent unintended pregnancy, future evaluations of antiretroviral prophylaxis will focus on methods of delivery (oral, topical [vaginal, rectal], injectable), regimens (daily, monthly, intermittent/exposure related, pre and post), single versus combination products, and what works in specific target populations (defined by risk, behaviour, and infection status).
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(10)61200-7