Fungal laccases: from structure-activity studies to environmental applications

Laccases are multicopper oxidases mainly secreted by filamentous fungi. Producing radical forms from organic substrates, they are involved in numerous reactions leading to the degradation and polymerization of xenobiotics. Our studies have led to a better knowledge of the structural, catalytic and g...

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Bibliographic Details
Published inEnvironmental chemistry letters Vol. 1; no. 2; pp. 145 - 148
Main Authors Mougin, Christian, Jolivalt, Claude, Briozzo, Pierre, Madzak, Catherine
Format Journal Article
LanguageEnglish
Published Dordrecht Springer Nature B.V 01.08.2003
Springer Verlag
Subjects
Bioremediation
Chemical and Process Engineering
Engineering Sciences
Environmental Sciences
Food engineering
Genetic engineering
Life Sciences
Microbiology
Organic compounds
Soil pollution
Xenobiotics
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Summary:Laccases are multicopper oxidases mainly secreted by filamentous fungi. Producing radical forms from organic substrates, they are involved in numerous reactions leading to the degradation and polymerization of xenobiotics. Our studies have led to a better knowledge of the structural, catalytic and genetic properties of laccases and allowed to develop a strategy for their evolution through genetic engineering. Here, we show that fungal laccases, wild or engineered, may be potent tools to develop bioremediation processes of soils polluted by organic compounds, and assays to assess the ecotoxicological impact of these pollutants on soil fungi.[PUBLICATION ABSTRACT]
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ISSN:1610-3653
1610-3661
DOI:10.1007/s10311-003-0024-9