The central role of Sertoli cells in spermatogenesis

• Published in: Seminars in cell & developmental biology Vol. 9; no. 4; pp. 411 - 416
• Main Author: Griswold, Michael D
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.1998
• Subjects: Animals; FSH, germ cells, Sertoli cells, testosterone, transferrin; Humans; Male; Sertoli Cells - cytology; Sertoli Cells - physiology; Spermatogenesis - physiology; FSH, germ cells, Sertoli cells, testosterone, transferrin

Sertoli cells are the somatic cells of the testis that are essential for testis formation and spermatogenesis. Sertoli cells facilitate the progression of germ cells to spermatozoa via direct contact and by controlling the environment milieu within the seminiferous tubules. The regulation of spermat...