Impact of Blood Transfusions in Patients Presenting With Anemia and Suspected Acute Coronary Syndrome
Anemia has been shown to predict adverse events in patients presenting with acute coronary syndromes and non–ST-elevation myocardial infarctions (MIs). Less is known about the value of blood transfusions in this setting. We sought to evaluate the impact of red blood cell transfusions on outcomes. Tr...
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Published in | The American journal of cardiology Vol. 99; no. 8; pp. 1119 - 1121 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
15.04.2007
Elsevier Limited |
Subjects | |
Online Access | Get full text |
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Summary: | Anemia has been shown to predict adverse events in patients presenting with acute coronary syndromes and non–ST-elevation myocardial infarctions (MIs). Less is known about the value of blood transfusions in this setting. We sought to evaluate the impact of red blood cell transfusions on outcomes. Transfusion in anemic patients admitted with suspected acute coronary syndrome/non–ST-elevation MIs led to a significant increase in 30-day recurrent MI or death (odds ratio 3.05, 95% confidence interval 1.80 to 5.17, p <0.001). This relation persisted after adjusting for significant univariate predictors: hypotension on presentation, pulmonary edema, and increased troponin-I levels (odds ratio 2.57, 95% confidence interval 1.41 to 4.69, p <0.001). In conclusion, the risk versus benefit of transfusion in patients presenting with an acute coronary syndrome needs careful assessment. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0002-9149 1879-1913 |
DOI: | 10.1016/j.amjcard.2006.11.056 |