Antiphospholipid antibodies and atherosclerosis: Insights from Rheumatoid arthritis – A five-year follow-up study

• Published in: Immunobiology (1979) Vol. 216; no. 12; pp. 1331 - 1337
• Main Authors: Holc, Iztok, Hojs, Radovan, Čikeš, Nada, Ambrožič, Aleš, Čučnik, Saša, Kveder, Tanja, Rozman, Blaž, Pahor, Artur
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier GmbH 01.12.2011
• Subjects: Adult; Advanced Basic Science; Allergy and Immunology; Antibodies, Antiphospholipid - blood; Apolipoproteins - blood; Arthritis, Rheumatoid - complications; Arthritis, Rheumatoid - diagnosis; Arthritis, Rheumatoid - immunology; Atherosclerosis; Atherosclerosis - complications; Atherosclerosis - diagnosis; Atherosclerosis - immunology; Atherosclerotic plaques; beta 2-Glycoprotein I - immunology; Carotid Intima-Media Thickness; Disease Progression; Female; Follow-Up Studies; Homocysteine; Homocysteine - blood; Humans; IgA anti-β 2 glycoprotein I antibodies; Immunoglobulin A - blood; Intima-media thickness; Middle Aged; Plaque, Atherosclerotic - pathology; Prognosis; Rheumatoid arthritis; Risk Factors; Ultrasonography; Intima-media thickness; Homocysteine; Rheumatoid arthritis; Atherosclerosis; Atherosclerotic plaques; IgA anti-β 2 glycoprotein I antibodies
• ISSN: 0171-2985; 1878-3279
• DOI: 10.1016/j.imbio.2011.05.008

Highlights ► Atherosclerosis is accelerated in selected group of female RA patients. ► We were not able to confirm that IgA anti-β2GPI may represent an independent risk factor for atherosclerosis. ► Homocysteine and Apo B have an important impact on the development of atherosclerosis in female RA patients.