A literature review on the potential clinical implications of streptococci in gastric cancer

Streptococcus is widely found in nature and the human body, and most species are not pathogenic. In recent years, studies have found that Streptococcus is associated with gastric cancer. Streptococcus was found to be enriched in the oral cavity, stomach and intestine of gastric cancer patients and f...

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Published inFrontiers in microbiology Vol. 13; p. 1010465
Main Authors Zi, Mengli, Zhang, Yanqiang, Hu, Can, Zhang, Shengjie, Chen, Jinxia, Yuan, Li, Cheng, Xiangdong
Format Journal Article
LanguageEnglish
Published Frontiers Media S.A 26.10.2022
Subjects
digestive tract
gastric cancer
Helicobacter pylori
Microbiology
oral
Streptococcus
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Summary:Streptococcus is widely found in nature and the human body, and most species are not pathogenic. In recent years, studies have found that Streptococcus is associated with gastric cancer. Streptococcus was found to be enriched in the oral cavity, stomach and intestine of gastric cancer patients and found to be increased in gastric cancer tissues, suggesting that Streptococcus may be the pathogenic bacteria underlying gastric cancer. This review discusses the discovery of Streptococcus, the relationship between Streptococcus and gastric cancer, and the possible carcinogenic mechanism of Streptococcus and summarizes the progress of the research on the role of Streptococcus in gastric cancer to provide new ideas for the early detection, diagnosis and treatment of gastric cancer.
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Edited by: Karolina Skonieczna-Żydecka, Pomeranian Medical University, Poland
Reviewed by: Tomasz M. Karpiński, Poznan University of Medical Sciences, Poland; Anastasios Koulaouzidis, University of Southern Denmark, Denmark
This article was submitted to Microorganisms in Vertebrate Digestive Systems, a section of the journal Frontiers in Microbiology
These authors share first authorship
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2022.1010465