Complete response to weekly carboplatin–docetaxel chemotherapy in a 91-year-old woman with anaplastic thyroid cancer

Abstract Anaplastic thyroid cancer (ATC) is an unusual tumor with the worst prognosis among thyroid malignancies. Treatment of the patients diagnosed with ATC is not standardized and the feasible options include surgery, radiotherapy and chemotherapy. ATC cannot be regarded as a very chemo-sensitive...

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Bibliographic Details
Published inAmerican journal of otolaryngology Vol. 36; no. 2; pp. 268 - 272
Main Authors Koussis, Haralabos, MD, Giorgi, Carlo Alberto, MD, Di Liso, Elisabetta, MD, Carlucci, Maria Concetta, Psy, Fassina, Ambrogio, MD, Marioni, Gino, MD, Conte, Pier Franco, MD
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.03.2015
Elsevier Limited
Subjects
Aged, 80 and over
Airway management
Antineoplastic Combined Chemotherapy Protocols - administration & dosage
Antineoplastic Combined Chemotherapy Protocols - adverse effects
Biological products
Biopsy, Fine-Needle
Cancer therapies
Carboplatin - administration & dosage
Chemotherapy
Clinical trials
Dose-Response Relationship, Drug
Drug Administration Schedule
Drug dosages
Female
Follow-Up Studies
Humans
Immunohistochemistry
Medical imaging
Medical prognosis
Metastasis
Neck
Otolaryngology
Patients
Positron-Emission Tomography - methods
Radiation therapy
Radiotherapy, Adjuvant
Rare Diseases
Remission Induction
Response rates
Surgery
Taxoids - administration & dosage
Thyroid cancer
Thyroid Carcinoma, Anaplastic - diagnostic imaging
Thyroid Carcinoma, Anaplastic - drug therapy
Thyroid Carcinoma, Anaplastic - pathology
Thyroid Carcinoma, Anaplastic - radiotherapy
Thyroid Neoplasms - diagnostic imaging
Thyroid Neoplasms - drug therapy
Thyroid Neoplasms - pathology
Thyroid Neoplasms - radiotherapy
Treatment Outcome
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Summary:Abstract Anaplastic thyroid cancer (ATC) is an unusual tumor with the worst prognosis among thyroid malignancies. Treatment of the patients diagnosed with ATC is not standardized and the feasible options include surgery, radiotherapy and chemotherapy. ATC cannot be regarded as a very chemo-sensitive tumor. Herein, we reported a case of a 91-year-old woman with complete response after induction chemotherapy (weekly carboplatin and docetaxel) that underwent subsequent radiotherapy.
Bibliography:ObjectType-Case Study-3
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ObjectType-Feature-5
ObjectType-Report-2
ObjectType-Article-4
ISSN:0196-0709
1532-818X
DOI:10.1016/j.amjoto.2014.03.006