miRNAFold: a web server for fast miRNA precursor prediction in genomes

Computational methods are required for prediction of non-coding RNAs (ncRNAs), which are involved in many biological processes, especially at post-transcriptional level. Among these ncRNAs, miRNAs have been largely studied and biologists need efficient and fast tools for their identification. In par...

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Bibliographic Details
Published inNucleic acids research Vol. 44; no. W1; pp. W181 - W184
Main Authors Tav, Christophe, Tempel, Sébastien, Poligny, Laurent, Tahi, Fariza
Format Journal Article
LanguageEnglish
Published England Oxford University Press 08.07.2016
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Summary:Computational methods are required for prediction of non-coding RNAs (ncRNAs), which are involved in many biological processes, especially at post-transcriptional level. Among these ncRNAs, miRNAs have been largely studied and biologists need efficient and fast tools for their identification. In particular, ab initio methods are usually required when predicting novel miRNAs. Here we present a web server dedicated for miRNA precursors identification at a large scale in genomes. It is based on an algorithm called miRNAFold that allows predicting miRNA hairpin structures quickly with high sensitivity. miRNAFold is implemented as a web server with an intuitive and user-friendly interface, as well as a standalone version. The web server is freely available at: http://EvryRNA.ibisc.univ-evry.fr/miRNAFold.
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ISSN:0305-1048
1362-4962
DOI:10.1093/nar/gkw459