Weight Loss in Underserved Patients — A Cluster-Randomized Trial

In this cluster-randomized trial, carried out in an underserved population, the authors hypothesized that a high-intensity lifestyle intervention would result in greater weight loss than usual care. Patients assigned to the high-intensity program lost significantly more weight than patients who rece...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 383; no. 10; pp. 909 - 918
Main Authors Katzmarzyk, Peter T, Martin, Corby K, Newton, Robert L, Apolzan, John W, Arnold, Connie L, Davis, Terry C, Price-Haywood, Eboni G, Denstel, Kara D, Mire, Emily F, Thethi, Tina K, Brantley, Phillip J, Johnson, William D, Fonseca, Vivian, Gugel, Jonathan, Kennedy, Kathleen B, Lavie, Carl J, Sarpong, Daniel F, Springgate, Benjamin
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 03.09.2020
Subjects
Adult
Age
Aged
Biomedical research
Body weight
Body weight loss
Cardiovascular disease
Clinics
Collaboration
Diabetes
Diet, Reducing
Exercise
Female
Gastrointestinal surgery
Health Literacy
Healthcare Disparities
Healthy Lifestyle
Humans
Hypotheses
Hypothesis testing
Intervention
Lifestyles
Male
Middle Aged
Nutrition
Obesity
Obesity - ethnology
Obesity - physiopathology
Obesity - therapy
Patient Education as Topic
Patient-centered care
Patients
Physical activity
Population
Primary care
Primary Health Care
Socioeconomic Factors
Vulnerable Populations
Weight control
Weight Loss
Young Adult
Louisiana
United States > US
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Summary:In this cluster-randomized trial, carried out in an underserved population, the authors hypothesized that a high-intensity lifestyle intervention would result in greater weight loss than usual care. Patients assigned to the high-intensity program lost significantly more weight than patients who received usual care.
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We thank the patients and the members of the patient advisory boards, community monitoring board, and the project management committee (Chris Lodge and Ava Zebrick, M.S.), who contributed greatly to the design and conduct of the trial; the trial patients, assessment technicians, and health coaches, without whom this trial would not have been possible; Willie C. White III, M.P.H., and the David Raines Community Health Centers; Gary Wiltz, M.D., and the Teche Action Clinic sites; Michael G. Griffin and Robert Post, M.D., and the Daughters of Charity Services of New Orleans; the Ochsner Health System and Access Health Louisiana clinic sites; the data and safety monitoring board (Robert Ross, Ph.D. [chair], John Lefante, Ph.D., Michael Rolfson, M.D., and Chris Lodge) for overseeing patient safety and the overall conduct of the trial; and David B. Allison, Ph.D., Andrew W. Brown, Ph.D., Stephanie L. Dickinson, M.S., and Lilian Golzarri-Arroyo, M.S., of the Indiana University School of Public Health–Bloomington for reviewing and verifying the statistical methods and results of this project.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa2007448