Guidelines of the International Headache Society for controlled trials of preventive treatment of chronic migraine in adults

Background Quality clinical trials form an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for Controlled Trials of Drugs in Migrain...

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Bibliographic Details
Published inCephalalgia Vol. 38; no. 5; pp. 815 - 832
Main Authors Tassorelli, Cristina, Diener, Hans-Christoph, Dodick, David W, Silberstein, Stephen D, Lipton, Richard B, Ashina, Messoud, Becker, Werner J, Ferrari, Michel D, Goadsby, Peter J, Pozo-Rosich, Patricia, Wang, Shuu-Jiun
Format Journal Article
LanguageEnglish
Published London, England SAGE Publications 01.04.2018
Subjects
Chronic migraine
clinical trials
headache
drugs
preventive treatment
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Summary:Background Quality clinical trials form an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for Controlled Trials of Drugs in Migraine. In 2008, the Committee published the first specific guidelines on chronic migraine. Subsequent advances in drug, device, and biologicals development, as well as novel trial designs, have created a need for a revision of the chronic migraine guidelines. Objective The present update is intended to optimize the design of controlled trials of preventive treatment of chronic migraine in adults, and its recommendations do not apply to trials in children or adolescents.
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ISSN:0333-1024
1468-2982
1468-2982
DOI:10.1177/0333102418758283