Fish-oil esters of plant sterols improve the lipid profile of dyslipidemic subjects more than do fish-oil or sunflower oil esters of plant sterols

• Published in: The American journal of clinical nutrition Vol. 84; no. 6; pp. 1534 - 1542
• Main Authors: Demonty, Isabelle, Chan, Yen-Ming, Pelled, Dori, Jones, Peter JH
• Format: Journal Article
• Language: English
• Published: Bethesda, MD American Society for Nutrition 01.12.2006; American Society for Clinical Nutrition; American Society for Clinical Nutrition, Inc
• Subjects: administration & dosage; Adult; Aged; Anticholesteremic Agents; Anticholesteremic Agents - therapeutic use; Apolipoproteins B; Apolipoproteins B - blood; Biological and medical sciences; blood; blood lipids; cholesteremic effect; Cholesterol; Cholesterol - blood; Cholesterol, HDL; Cholesterol, HDL - blood; Cholesterol, LDL; Cholesterol, LDL - blood; Cross-Over Studies; Diet; Dietary Fats, Unsaturated; Dietary Fats, Unsaturated - administration & dosage; Dietary Supplements; Docosahexaenoic Acids; Docosahexaenoic Acids - administration & dosage; drug therapy; Eicosapentaenoic Acid; Eicosapentaenoic Acid - administration & dosage; Esters; experimental diets; fatty acid esters; Fatty acids; Fatty Acids, Omega-3; Fatty Acids, Omega-3 - administration & dosage; Feeding. Feeding behavior; Female; Fish oils; Fish Oils - administration & dosage; Functional foods & nutraceuticals; Fundamental and applied biological sciences. Psychology; human nutrition; Humans; Hypercholesterolemia; Hypercholesterolemia - drug therapy; hyperlipidemia; Lipids; Male; men; menopause; Middle Aged; Nutrition; Olive Oil; Phytosterols; Phytosterols - therapeutic use; Plant Oils; Plant Oils - administration & dosage; Sunflower Oil; therapeutic use; Triglycerides; Triglycerides - blood; Vertebrates: anatomy and physiology, studies on body, several organs or systems; women; Cardiovascular disease; Lipids; cardiovascular risk factors; plasma lipids; Blood plasma; Vascular disease; Ester; Plant; Sunflower oil; Triacylglycerol; Cholesterol HDL; Atherosclerosis; n-3 polyunsaturated fatty acids; Dyslipemia; Human; Polyunsaturated fatty acid; Metabolic diseases; Cholesterol LDL; Apolipoprotein; Olive oil; Apolipoproteins; Fish oil; HDL cholesterol; plant sterols; Risk factor; triacylglycerols; LDL cholesterol; Sterol

BACKGROUND: Fish-oil fatty acid esters of plant sterols (FO-PS) were shown to have hypotriglyceridemic and hypocholesterolemic properties in animal models. OBJECTIVE: The objective of the study was to evaluate the hypolipidemic effects of FO-PS supplementation in healthy hypercholesterolemic persons...