Early detection of the SARS-CoV-2 P.1 variant in Rio Grande do Sul, Brazil: a case report

To the Editor—In December 2019, a new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China and was associated with coronavirus disease 2019 (COVID-19). Since it was first described, multiple lineages of SARS-CoV-2 have been identified worldwide. According to Pa...

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Published inInfection Control & Hospital Epidemiology Vol. 43; no. 12; pp. 1997 - 1999
Main Authors Volpato, Fabiana Caroline Zempulski, Wink, Priscila Lamb, Monteiro, Francielle Liz, Willig, Julia Biz, Vieceli, Tarsila, Martins, Andreza Francisco, Zavascki, Alexandre Prehn, Barth, Afonso Luís
Format Journal Article
LanguageEnglish
Published New York, USA Cambridge University Press 01.12.2022
Subjects
Amino acids
Brazil - epidemiology
Coronaviruses
COVID-19
COVID-19 - diagnosis
Early Diagnosis
Genomes
Genomics
Hospitalization
Humans
Letter to the Editor
Mutation
Proteins
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Viral infections
Brazil
Rio Grande do Sul Brazil
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Summary:To the Editor—In December 2019, a new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China and was associated with coronavirus disease 2019 (COVID-19). Since it was first described, multiple lineages of SARS-CoV-2 have been identified worldwide. According to Pangolin,4 the VOC P1 is characterized by 17 amino acid changes (including 10 in the spike protein), 3 deletions, 4 synonymous mutations, and one 4-bp nucleotide insertion compared to the most closely related sequence of B.1.1.28 available from April 4, 2020 (GISAID ID: [...]genomic surveillance is a fundamental tool for understanding the evolution and spread of SARS-CoV-2 variants.
ISSN:0899-823X
1559-6834
DOI:10.1017/ice.2021.387