Serological Profile for Major Respiratory Viruses in Unvaccinated Cows from High-Yielding Dairy Herds

• Published in: Animals (Basel) Vol. 14; no. 9; p. 1256
• Main Authors: Yoshitani, Geovana Depieri, Camilo, Stefany Lia Oliveira, Fritzen, Juliana Torres Tomazi, Oliveira, Marcos Vinicius, Lorenzetti, Elis, Lisbôa, Julio Augusto Naylor, Alfieri, Alice Fernandes, Alfieri, Amauri Alcindo
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.05.2024
• Subjects: Animals; Antibodies; Bacterial infections; Beef; Biological products; bovine alphaherpesvirus 1; bovine parainfluenza virus 3; bovine respiratory syncytial virus; bovine viral diarrhea virus; Dairy cattle; Infections; Livestock; Lung diseases; Milk production; Pneumonia; Prevention; Serology; Viral antibodies; Virus diseases; virus neutralization test; Viruses; Brazil; bovine alphaherpesvirus 1; virus neutralization test; bovine viral diarrhea virus; bovine parainfluenza virus 3; bovine respiratory syncytial virus; serology
• ISSN: 2076-2615; 2076-2615
• DOI: 10.3390/ani14091256

This study aims to determine the serological profile of high-yielding dairy cows for four main viruses (bovine alphaherpesvirus 1 (BoAHV1), bovine viral diarrhea virus (BVDV), bovine parainfluenza virus 3 (BPIV3), and bovine respiratory syncytial virus (BRSV)) related to bovine respiratory disease (BRD) in cattle herds worldwide. In this survey, 497 blood serum samples were collected from non-vaccinated dairy cows without clinical respiratory signs in 39 herds in the central-eastern mesoregion of Paraná State, South Brazil. The presence of neutralizing antibodies was determined by virus neutralization (VN) tests. VN antibodies against BoAHV1, BVDV, BPIV3, and BRSV were detected in 355 (71.4%), 280 (56.3%), 481 (96.8%), and 315 (63.4%) serum samples, respectively. The frequencies of seropositive herds for BoAHV1, BVDV, BPIV3, and BRSV were 79.5 ( = 31), 82.0 ( = 32), 100 ( = 39), and 84.6% ( = 33), respectively. The frequencies of seropositive cows varied according to the type of herd management and the number of cows in the herd. The detection of VN antibodies in unvaccinated dairy cattle herds demonstrated the endemic circulation of the four viruses in the herds evaluated. For BRD prevention, it is recommended to implement a vaccination program for cows that provides passive immunity in calves and active immunity in cows.