Intravenous leiomyomatosis with intracardiac extension – A review of diagnosis and management with an illustrative case

Abstract Intravenous leiomyomatosis with intracardiac extension is an uncommon pathologic progression of uterine leiomyomata. It is a histologically benign condition, however due to interfence with right sided cardiac function patients may present with marked cardiovascular compromise and present a...

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Published inSurgical oncology Vol. 22; no. 3; pp. e44 - e52
Main Authors Clay, Timothy D, Dimitriou, Jim, McNally, Orla M, Russell, Prudence A, Newcomb, Andrew E, Wilson, Andrew M
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.09.2013
Elsevier Limited
Subjects
Abdomen
Adult
Cardiac arrhythmia
Cardiac tumours
Female
Fibroids
Heart Neoplasms - diagnosis
Heart Neoplasms - surgery
Hematology, Oncology and Palliative Medicine
Hospitals
Humans
Intravenous leiomyomatosis
Leiomyomatosis - diagnosis
Leiomyomatosis - surgery
Magnetic Resonance Imaging
Medical imaging
Mortality
NMR
Nuclear magnetic resonance
Patients
Prognosis
Pulmonary arteries
Surgery
Uterine Neoplasms - diagnosis
Uterine Neoplasms - surgery
Veins & arteries
Vena Cava, Inferior - pathology
Womens health
Cardiac tumours
Surgery
Intravenous leiomyomatosis
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Summary:Abstract Intravenous leiomyomatosis with intracardiac extension is an uncommon pathologic progression of uterine leiomyomata. It is a histologically benign condition, however due to interfence with right sided cardiac function patients may present with marked cardiovascular compromise and present a diagnostic dilemma to clinicians who are unfamiliar with this condition. Given the rarity of this condition, experience in individual institutions is usually limited to a few cases. We present an illustrative case and provide a review of the clinical presentation, preoperative assessment, operative approach, pathology and postoperative issues. The importance of a multidisciplinary approach to diagnosis and management is highlighted. Operative management aims to completely resect all tumour in the safest manner for the patient, most commonly via single or two stage operation. Where complete resection is achieved, recurrence appears to be a rare event.
Bibliography:ObjectType-Case Study-3
SourceType-Scholarly Journals-1
content type line 23
ObjectType-Review-1
ObjectType-Feature-5
ObjectType-Report-2
ObjectType-Article-4
ISSN:0960-7404
1879-3320
DOI:10.1016/j.suronc.2013.03.004