Polymorphisms in DNA repair and multidrug resistance genes among Sindhis of Central India
Highlights • India is one of the most ethnically and genetically diverse regions of the world. • 6 SNPs in DNA repair and multidrug resistance genes were studied in Indian Sindhis. • These SNPs could influence susceptibility to cancer and drug disposition. • We determined the allele and genotype fre...
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Published in | Environmental toxicology and pharmacology Vol. 40; no. 2; pp. 480 - 485 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier B.V
01.09.2015
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Subjects | |
Online Access | Get full text |
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Summary: | Highlights • India is one of the most ethnically and genetically diverse regions of the world. • 6 SNPs in DNA repair and multidrug resistance genes were studied in Indian Sindhis. • These SNPs could influence susceptibility to cancer and drug disposition. • We determined the allele and genotype frequencies of these SNPs in Indian Sindhis. • Sindhis were closely related to Maharshtrians and some other HapMap populations. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1382-6689 1872-7077 |
DOI: | 10.1016/j.etap.2015.07.019 |